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- W2553600543 abstract "Summary The Revised Metabolic Oncolytic Regimen is based on an approach to achieving lysis in solid tumors pioneered by Clarence Cone, Jr., Ph.D. (NASA, retired). Dr. Cone's novel therapy, which is reflected in patents granted various versions of same [U.S. patent #s 4,724,230 (1988), 4,724,234 (1988), and 4,935,450 (1990)] essentially involves manipulating various metabolic and biochemical pathways such that tumors produce prodigious quantities of lactic acid. This is achieved using a specific dietary regimen plus various synthetic and natural drugs, e.g., the bioflavonoid quercitin is employed to block export of lactate from the tumor which results in a lethal drop in intratumor pH. [The Cone therapy involves two treatment phases with a resting or nontreatment interval between them]. The principle shortcoming of the Cone therapy lies in the fact that it is hypoxic clusters within certain solid tumors - and not the entire tumor - which synthesizes and exports lactic acid" @default.
- W2553600543 created "2016-11-30" @default.
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- W2553600543 date "2011-01-01" @default.
- W2553600543 modified "2023-09-27" @default.
- W2553600543 title "The Metabolic Oncolytic Regimen For Effecting Lysis in Solid Tumors (Revised 2011)" @default.
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