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- W2553617367 abstract "Background: Helicobacter pylori is involved in the pathogenesis of peptic ulcer disease and associated with gastric carcinoma. It has been classified as a definite class I carcinogen by the World Health Organization. the prevalence of H. pylori infection may exceed 70% in some developing countries. An 5important virulence determinant H. pylori is vacuolating cytotoxin (VacA), which induces cytoplasmic vacuolation and produces epithelial cell damage and mucosal ulceration. This study was conducted to determine the frequency of Helicobacter pylori vacA genotypes in patients with gastroduodenitis and peptic ulcer from Khartoum, Sudan. Methods: A total of fifty seven (n=57) patients with gastroduodenitis and peptic ulcer were enrolled in this study, they were collected during endoscopy by the gastroenterologists. Twelve (n=12)" @default.
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- W2553617367 date "2015-01-01" @default.
- W2553617367 modified "2023-09-24" @default.
- W2553617367 title "The Frequency of Helicobacter pylori vacA producing genotypes in patients with gastroduodenitis and peptic ulcer from Khartoum, Sudan" @default.
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