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- W2553627369 abstract "Background: Cigarette Smoke (CS) and Chorine gas (Cl2),found in cleaning products (sodium hypochlorite-NaClO), are involved in pulmonary diseases. There is a high prevalence of smoking among cleaning workers. These factors may be stressors causing behavior alterations. Objective: To investigate effects of NaClO and CS on lung function and behavior of Wistar rats. Methods:Experimental groups (n=8/each) were:1:Control(C),2:Cigarette Smoke(CS), 3:Hypochlorite(H),4:Cigarette Smoke+Hypochlorite(CSH).Weassessed:behavior usingElevated Plus-Maze (EPM), lung mechanics, bronchoalveolar lavage fluid (BALF), mean linear intercept (LM), airway infiltrate and remodeling. Results:BALF total cells were increased in CS, H and CSH, neutrophils in H and macrophages in CS and CSH compared to C(p Conclusion:Cigarette smoke and hypochlorite increase lung inflammation andairwayedema. Co-exposure to CS and NaClO causes airwayremodeling associated to an attenuation of inflammation.The behavior alterations observed suggest that CS or theco-exposure to CS and NaClO were potential stressors for these animals." @default.
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- W2553627369 date "2016-09-01" @default.
- W2553627369 modified "2023-09-24" @default.
- W2553627369 title "Effects of sodium hypochlorite and cigarette smoke on lung function and behavior of Wistar rats" @default.
- W2553627369 doi "https://doi.org/10.1183/13993003.congress-2016.oa3503" @default.
- W2553627369 hasPublicationYear "2016" @default.
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