FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2553676369> ?p ?o ?g. }

• W2553676369 endingPage "e0166699" @default.
• W2553676369 startingPage "e0166699" @default.
• W2553676369 abstract "In a markedly seasonal malaria setting, the transition from the transmission-free dry season to the transmission season depends on the resurgence of the mosquito population following the start of annual rains. The sudden onset of malaria outbreaks at the start of the transmission season suggests that parasites persist during the dry season and respond to either the reappearance of vectors, or correlated events, by increasing the production of transmission stages. Here, we investigate whether Plasmodium falciparum gametocyte density and the correlation between gametocyte density and parasite density show seasonal variation in chronic (largely asymptomatic) carriers in eastern Sudan.We recruited and treated 123 malaria patients in the transmission season 2001. We then followed them monthly during four distinct consecutive epidemiological seasons: transmission season 1, transmission-free season, pre-clinical period, and transmission season 2. In samples collected from 25 participants who fulfilled the selection criteria of the current analysis, we used quantitative PCR (qPCR) and RT-qPCR to quantify parasite and gametocyte densities, respectively.We observed a significant increase in gametocyte density and a significantly steeper positive correlation between gametocyte density and total parasite density during the pre-clinical period compared to the preceding transmission-free season. However, there was no corresponding increase in the density or prevalence of total parasites or gametocyte prevalence. The increase in gametocyte production during the pre-clinical period supports the hypothesis that P. falciparum may respond to environmental cues, such as mosquito biting, to modulate its transmission strategy. Thus, seasonal changes may be important to ignite transmission in unstable-malaria settings." @default.
• W2553676369 created "2016-11-30" @default.
• W2553676369 creator A5007197867 @default.
• W2553676369 creator A5012573739 @default.
• W2553676369 creator A5038439031 @default.
• W2553676369 creator A5040271212 @default.
• W2553676369 creator A5074805566 @default.
• W2553676369 creator A5078403324 @default.
• W2553676369 creator A5085627828 @default.
• W2553676369 creator A5089381738 @default.
• W2553676369 date "2016-11-21" @default.
• W2553676369 modified "2023-10-17" @default.
• W2553676369 title "Associations between Season and Gametocyte Dynamics in Chronic Plasmodium falciparum Infections" @default.
• W2553676369 cites W14415935 @default.
• W2553676369 cites W1829949460 @default.
• W2553676369 cites W1948731308 @default.
• W2553676369 cites W1963888047 @default.
• W2553676369 cites W1969128418 @default.
• W2553676369 cites W1971844738 @default.
• W2553676369 cites W1987368684 @default.
• W2553676369 cites W1989846502 @default.
• W2553676369 cites W1993435564 @default.
• W2553676369 cites W1994266253 @default.
• W2553676369 cites W1997667617 @default.
• W2553676369 cites W2001711014 @default.
• W2553676369 cites W2008672550 @default.
• W2553676369 cites W2008993634 @default.
• W2553676369 cites W2016828296 @default.
• W2553676369 cites W2022276896 @default.
• W2553676369 cites W2027057850 @default.
• W2553676369 cites W2028091256 @default.
• W2553676369 cites W2028626843 @default.
• W2553676369 cites W2029237652 @default.
• W2553676369 cites W2032882643 @default.
• W2553676369 cites W2042573261 @default.
• W2553676369 cites W2046121385 @default.
• W2553676369 cites W2048958484 @default.
• W2553676369 cites W2051373294 @default.
• W2553676369 cites W2055742521 @default.
• W2553676369 cites W2062280173 @default.
• W2553676369 cites W2092201106 @default.
• W2553676369 cites W2093478166 @default.
• W2553676369 cites W2094048666 @default.
• W2553676369 cites W2104386816 @default.
• W2553676369 cites W2111166381 @default.
• W2553676369 cites W2112977667 @default.
• W2553676369 cites W2116350812 @default.
• W2553676369 cites W2116560236 @default.
• W2553676369 cites W2117770117 @default.
• W2553676369 cites W2124398835 @default.
• W2553676369 cites W2127893137 @default.
• W2553676369 cites W2131545842 @default.
• W2553676369 cites W2140931333 @default.
• W2553676369 cites W2149575909 @default.
• W2553676369 cites W2155180028 @default.
• W2553676369 cites W2159054466 @default.
• W2553676369 cites W2159878978 @default.
• W2553676369 cites W2161657947 @default.
• W2553676369 cites W2162423316 @default.
• W2553676369 cites W2167379819 @default.
• W2553676369 cites W2167552649 @default.
• W2553676369 cites W2167828684 @default.
• W2553676369 cites W2169059629 @default.
• W2553676369 cites W2286637160 @default.
• W2553676369 cites W2416319109 @default.
• W2553676369 cites W4246757520 @default.
• W2553676369 cites W66070344 @default.
• W2553676369 cites W2148314756 @default.
• W2553676369 doi "https://doi.org/10.1371/journal.pone.0166699" @default.
• W2553676369 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5117706" @default.
• W2553676369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27870874" @default.
• W2553676369 hasPublicationYear "2016" @default.
• W2553676369 type Work @default.
• W2553676369 sameAs 2553676369 @default.
• W2553676369 citedByCount "22" @default.
• W2553676369 countsByYear W25536763692017 @default.
• W2553676369 countsByYear W25536763692018 @default.
• W2553676369 countsByYear W25536763692019 @default.
• W2553676369 countsByYear W25536763692020 @default.
• W2553676369 countsByYear W25536763692021 @default.
• W2553676369 crossrefType "journal-article" @default.
• W2553676369 hasAuthorship W2553676369A5007197867 @default.
• W2553676369 hasAuthorship W2553676369A5012573739 @default.
• W2553676369 hasAuthorship W2553676369A5038439031 @default.
• W2553676369 hasAuthorship W2553676369A5040271212 @default.
• W2553676369 hasAuthorship W2553676369A5074805566 @default.
• W2553676369 hasAuthorship W2553676369A5078403324 @default.
• W2553676369 hasAuthorship W2553676369A5085627828 @default.
• W2553676369 hasAuthorship W2553676369A5089381738 @default.
• W2553676369 hasBestOaLocation W25536763691 @default.
• W2553676369 hasConcept C116675565 @default.
• W2553676369 hasConcept C119599485 @default.
• W2553676369 hasConcept C127413603 @default.
• W2553676369 hasConcept C159047783 @default.
• W2553676369 hasConcept C18903297 @default.
• W2553676369 hasConcept C199733313 @default.
• W2553676369 hasConcept C203014093 @default.
• W2553676369 hasConcept C2778048844 @default.

• next