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- W2553696525 abstract "Background: Intensive exercise may affect the innate immunity, influence inflammatory response and increase susceptibility to respiratory infections. Aim: To assess if exercise modifies expression of innate immune response molecules in peripheral blood leukocytes (PBL) of competitive athletes, asthmatics and healthy subjects. Methods: Study included 15 athletes (speed skaters and swimmers), 9 mild-to-moderate asthmatics (AC) and 7 healthy non-exercising subjects (HC).Treadmill exercise challenge was done and PBLs were isolated before, immediately after and 1 hour post-exercise. Following RNA isolation relative gene expression was assessed by qPCR and calculated using 2 -Δ ΔCt method with pre-exercise expression as reference. Results: Significant decrease in mRNA expression immediately post-exercise was observed for IL-1ra in athletes (mean decrease 72%;p Conclusions: Acute exercise decreases innate immune response in PBLs to similar extent in competitive athletes and healthy subjects." @default.
- W2553696525 created "2016-11-30" @default.
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- W2553696525 date "2016-09-01" @default.
- W2553696525 modified "2023-10-17" @default.
- W2553696525 title "Treadmill exercise decreases expression of innate immunity molecules in peripheral blood leukocytes in competitive athletes, asthmatics and healthy subjects" @default.
- W2553696525 doi "https://doi.org/10.1183/13993003.congress-2016.pa571" @default.
- W2553696525 hasPublicationYear "2016" @default.
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