Matches in SemOpenAlex for { <https://semopenalex.org/work/W2553813565> ?p ?o ?g. }
- W2553813565 abstract "Histone Deacetylase (HDAC) inhibitors are an exciting new class of drugs that are targeted as anti- cancer agents. These compounds can induce growth arrest, apoptosis and/ or terminal differentiation in a variety of solid and hematological neoplasms in patients with advanced disease. Accumulation of acetylated histones in both normal and tumour cells can be used as a marker of biological activity. Hydroxamic acid based compounds are among the most promising HDAC inhibitors as potential anti-cancer drugs. There is still much to be understood about the family of HDACs, including the varying functions of different HDACs and the range of HDAC substrates. The development of selective HDAC inhibitors might be important in defining their biological role and potential as therapeutic agents. Clinically, the optimal dose, timing and duration of therapy, as well as the most appropriate agents to combine with HDAC inhibitors, are still to be defined." @default.
- W2553813565 created "2016-11-30" @default.
- W2553813565 creator A5034849712 @default.
- W2553813565 creator A5042433066 @default.
- W2553813565 creator A5051618308 @default.
- W2553813565 creator A5064992008 @default.
- W2553813565 creator A5072702667 @default.
- W2553813565 date "2015-01-01" @default.
- W2553813565 modified "2023-09-27" @default.
- W2553813565 title "Histone Deacetylase Inhibitor as a Novel Anticancer Agent: A Review" @default.
- W2553813565 cites W1486948598 @default.
- W2553813565 cites W1494847658 @default.
- W2553813565 cites W1500148822 @default.
- W2553813565 cites W1509466986 @default.
- W2553813565 cites W1534598827 @default.
- W2553813565 cites W1544547269 @default.
- W2553813565 cites W1550565578 @default.
- W2553813565 cites W1563624749 @default.
- W2553813565 cites W1592975144 @default.
- W2553813565 cites W1609412760 @default.
- W2553813565 cites W1677658690 @default.
- W2553813565 cites W1820010991 @default.
- W2553813565 cites W191946090 @default.
- W2553813565 cites W1920602060 @default.
- W2553813565 cites W1976967609 @default.
- W2553813565 cites W1982619775 @default.
- W2553813565 cites W1988688335 @default.
- W2553813565 cites W1992321786 @default.
- W2553813565 cites W1998006710 @default.
- W2553813565 cites W2000219496 @default.
- W2553813565 cites W2003369761 @default.
- W2553813565 cites W2005908911 @default.
- W2553813565 cites W2012968783 @default.
- W2553813565 cites W2034420402 @default.
- W2553813565 cites W2036639816 @default.
- W2553813565 cites W2042327228 @default.
- W2553813565 cites W2060300649 @default.
- W2553813565 cites W2070829831 @default.
- W2553813565 cites W2072375912 @default.
- W2553813565 cites W2079029980 @default.
- W2553813565 cites W2089425549 @default.
- W2553813565 cites W2101092227 @default.
- W2553813565 cites W2102900566 @default.
- W2553813565 cites W2103721535 @default.
- W2553813565 cites W2107733280 @default.
- W2553813565 cites W2109690522 @default.
- W2553813565 cites W2118972462 @default.
- W2553813565 cites W2132133628 @default.
- W2553813565 cites W2145109415 @default.
- W2553813565 cites W2170918883 @default.
- W2553813565 cites W2327522594 @default.
- W2553813565 cites W2338927555 @default.
- W2553813565 cites W636958816 @default.
- W2553813565 cites W2569844665 @default.
- W2553813565 cites W3147892054 @default.
- W2553813565 hasPublicationYear "2015" @default.
- W2553813565 type Work @default.
- W2553813565 sameAs 2553813565 @default.
- W2553813565 citedByCount "0" @default.
- W2553813565 crossrefType "journal-article" @default.
- W2553813565 hasAuthorship W2553813565A5034849712 @default.
- W2553813565 hasAuthorship W2553813565A5042433066 @default.
- W2553813565 hasAuthorship W2553813565A5051618308 @default.
- W2553813565 hasAuthorship W2553813565A5064992008 @default.
- W2553813565 hasAuthorship W2553813565A5072702667 @default.
- W2553813565 hasConcept C104317684 @default.
- W2553813565 hasConcept C119157956 @default.
- W2553813565 hasConcept C121608353 @default.
- W2553813565 hasConcept C142354902 @default.
- W2553813565 hasConcept C185592680 @default.
- W2553813565 hasConcept C27253355 @default.
- W2553813565 hasConcept C2776281265 @default.
- W2553813565 hasConcept C2778305200 @default.
- W2553813565 hasConcept C4951695 @default.
- W2553813565 hasConcept C502942594 @default.
- W2553813565 hasConcept C54355233 @default.
- W2553813565 hasConcept C55493867 @default.
- W2553813565 hasConcept C64927066 @default.
- W2553813565 hasConcept C71240020 @default.
- W2553813565 hasConcept C86803240 @default.
- W2553813565 hasConcept C98274493 @default.
- W2553813565 hasConceptScore W2553813565C104317684 @default.
- W2553813565 hasConceptScore W2553813565C119157956 @default.
- W2553813565 hasConceptScore W2553813565C121608353 @default.
- W2553813565 hasConceptScore W2553813565C142354902 @default.
- W2553813565 hasConceptScore W2553813565C185592680 @default.
- W2553813565 hasConceptScore W2553813565C27253355 @default.
- W2553813565 hasConceptScore W2553813565C2776281265 @default.
- W2553813565 hasConceptScore W2553813565C2778305200 @default.
- W2553813565 hasConceptScore W2553813565C4951695 @default.
- W2553813565 hasConceptScore W2553813565C502942594 @default.
- W2553813565 hasConceptScore W2553813565C54355233 @default.
- W2553813565 hasConceptScore W2553813565C55493867 @default.
- W2553813565 hasConceptScore W2553813565C64927066 @default.
- W2553813565 hasConceptScore W2553813565C71240020 @default.
- W2553813565 hasConceptScore W2553813565C86803240 @default.
- W2553813565 hasConceptScore W2553813565C98274493 @default.
- W2553813565 hasLocation W25538135651 @default.
- W2553813565 hasOpenAccess W2553813565 @default.
- W2553813565 hasPrimaryLocation W25538135651 @default.