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• W2554119129 abstract "The present investigation was aimed to study the effect of hexane fraction of seed extract of Melia azedarach Linn. (Family: Meliaceae) on estrous cycle, fertility and implantation in female albino rats @1mg, 3mg, 6mg, 12mg, 24mg/kg body weight. Fertility index and average number of embryos were considerably reduced in the adult cycling rats after 18 days of treatment @6mg, 12mg and 24mg/kg b.wt. However, the occurrence of various stages of estrous cycle was not disturbed significantly in the treated rats. Pre- implantation, post-implantation and total prenatal mortality was significantly increased in the treatment group (24mg/kg b.wt.) as compared to control during D1-D7pc and D7-D18pc treatments. The average gestation period was increased by about 9.5 days, where as litter size, live birth index and average life span of young ones @24mg/kg b.wt. decreased considerably. Thus, the results indicate that the hexane fraction of M. azedarach can be used as a fertility regulating agent as it possess antifertility, anti-implantation / abortive activity that may be attributed to its antiestrogenic property resulting in hormonal imbalance creating an unfavorable uterine environment for nidation." @default.
• W2554119129 created "2016-11-30" @default.
• W2554119129 creator A5033447289 @default.
• W2554119129 creator A5039907498 @default.
• W2554119129 date "2015-01-01" @default.
• W2554119129 modified "2023-09-26" @default.
• W2554119129 title "Effect of Melia azedarach Linn. Seed Extract on Estrous Cycle and Reproductive Performance in Female Rats" @default.
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• W2554119129 hasPublicationYear "2015" @default.
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