FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2554159443> ?p ?o ?g. }

• W2554159443 endingPage "636" @default.
• W2554159443 startingPage "629" @default.
• W2554159443 abstract "Systematic reviews comparing treatment of early glottic cancer with transoral surgery or radiotherapy demonstrate similar oncological outcomes. Most studies of 'early-stage' laryngeal cancer include Tis, T1a, T1b and T2 cases. The data are dominated by patients with T1 and Tis tumours, although extrapolating these results and applying them for T2 cases may be inappropriate. No previous systematic reviews have focused on T2 cancers as a separate group.This review compares local control outcomes for T2 glottic squamous cell carcinoma, treated with transoral microsurgery or external beam radiotherapy.This is a systematic review of case series and comparison studies, focusing on oncological outcomes.Independent searches of MEDLINE, EMBASE and the Cochrane Database were conducted by two authors, using the search terms: laryngeal/glottic/vocal cord combined with carcinoma/cancer/tumour and laser/microsurgery or radiotherapy. Studies of adult patients treated for primary T2N0 glottic squamous cell carcinoma (SCC) with laser surgery or curative radiotherapy were included.Full text of studies satisfying the inclusion criteria were reviewed with extraction of local control and survival data and laryngeal preservation rates. The primary endpoint is local control at 5 years.Initial searches identified 3252 studies. Following full-text review of 183 papers, 59 studies met the inclusion criteria, all level IV evidence. A total of 48 studies specified 5-year local control for 1156 patients treated with transoral laser surgery and 3191 patients treated with radiotherapy. Weighted averages of local control at 5 years demonstrated similar results: 75.81% for radiotherapy versus 77.26% for transoral laser surgery.The results of this review indicate no difference in 5-year local control between radiotherapy and transoral surgery for T2 glottic SCC. The data demonstrated higher rates of local failure for T2b compared with T2a cases, although outcomes were similar between laser excision and radiotherapy for each substage. Further research focusing upon functional outcomes for T2 glottic tumours is imperative to guide decision-making, ideally with subgroup analysis of T2a and T2b cases." @default.
• W2554159443 created "2016-11-30" @default.
• W2554159443 creator A5032346728 @default.
• W2554159443 creator A5051708028 @default.
• W2554159443 creator A5065588815 @default.
• W2554159443 date "2016-12-04" @default.
• W2554159443 modified "2023-10-14" @default.
• W2554159443 title "Transoral laser microsurgery <i>versus</i> radiotherapy for T2 glottic squamous cell carcinoma: a systematic review of local control outcomes" @default.
• W2554159443 cites W1495470173 @default.
• W2554159443 cites W1509294517 @default.
• W2554159443 cites W1560086478 @default.
• W2554159443 cites W1817853561 @default.
• W2554159443 cites W1918164105 @default.
• W2554159443 cites W1923845770 @default.
• W2554159443 cites W1933444341 @default.
• W2554159443 cites W1945073462 @default.
• W2554159443 cites W1948446007 @default.
• W2554159443 cites W1950698100 @default.
• W2554159443 cites W1967877405 @default.
• W2554159443 cites W1969611773 @default.
• W2554159443 cites W1979820641 @default.
• W2554159443 cites W1980729808 @default.
• W2554159443 cites W1986375524 @default.
• W2554159443 cites W1988621237 @default.
• W2554159443 cites W1989396963 @default.
• W2554159443 cites W2001688738 @default.
• W2554159443 cites W2006834181 @default.
• W2554159443 cites W2008241610 @default.
• W2554159443 cites W2012826574 @default.
• W2554159443 cites W2021106631 @default.
• W2554159443 cites W2024575583 @default.
• W2554159443 cites W2025652112 @default.
• W2554159443 cites W2028921704 @default.
• W2554159443 cites W2033984332 @default.
• W2554159443 cites W2035567192 @default.
• W2554159443 cites W2037259629 @default.
• W2554159443 cites W2042713192 @default.
• W2554159443 cites W2044535517 @default.
• W2554159443 cites W2051700187 @default.
• W2554159443 cites W2056720525 @default.
• W2554159443 cites W2061297112 @default.
• W2554159443 cites W2061363283 @default.
• W2554159443 cites W2062776583 @default.
• W2554159443 cites W2066811320 @default.
• W2554159443 cites W2070673821 @default.
• W2554159443 cites W2075800877 @default.
• W2554159443 cites W2076752093 @default.
• W2554159443 cites W2082632018 @default.
• W2554159443 cites W2084237805 @default.
• W2554159443 cites W2085621359 @default.
• W2554159443 cites W2088132024 @default.
• W2554159443 cites W2090968528 @default.
• W2554159443 cites W2093268394 @default.
• W2554159443 cites W2095648602 @default.
• W2554159443 cites W2098020551 @default.
• W2554159443 cites W2098581441 @default.
• W2554159443 cites W2100572002 @default.
• W2554159443 cites W2111740844 @default.
• W2554159443 cites W2115630690 @default.
• W2554159443 cites W2116116174 @default.
• W2554159443 cites W2125294251 @default.
• W2554159443 cites W2129572031 @default.
• W2554159443 cites W2131624236 @default.
• W2554159443 cites W2134962231 @default.
• W2554159443 cites W2140843986 @default.
• W2554159443 cites W2143231564 @default.
• W2554159443 cites W2152291399 @default.
• W2554159443 cites W2163138489 @default.
• W2554159443 cites W2169083232 @default.
• W2554159443 cites W2175408594 @default.
• W2554159443 cites W2312609029 @default.
• W2554159443 cites W2420143986 @default.
• W2554159443 cites W4240016060 @default.
• W2554159443 doi "https://doi.org/10.1111/coa.12790" @default.
• W2554159443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27863075" @default.
• W2554159443 hasPublicationYear "2016" @default.
• W2554159443 type Work @default.
• W2554159443 sameAs 2554159443 @default.
• W2554159443 citedByCount "60" @default.
• W2554159443 countsByYear W25541594432017 @default.
• W2554159443 countsByYear W25541594432018 @default.
• W2554159443 countsByYear W25541594432019 @default.
• W2554159443 countsByYear W25541594432020 @default.
• W2554159443 countsByYear W25541594432021 @default.
• W2554159443 countsByYear W25541594432022 @default.
• W2554159443 countsByYear W25541594432023 @default.
• W2554159443 crossrefType "journal-article" @default.
• W2554159443 hasAuthorship W2554159443A5032346728 @default.
• W2554159443 hasAuthorship W2554159443A5051708028 @default.
• W2554159443 hasAuthorship W2554159443A5065588815 @default.
• W2554159443 hasConcept C121608353 @default.
• W2554159443 hasConcept C126322002 @default.
• W2554159443 hasConcept C141071460 @default.
• W2554159443 hasConcept C2776530083 @default.
• W2554159443 hasConcept C2776957994 @default.
• W2554159443 hasConcept C2777546739 @default.
• W2554159443 hasConcept C2778993000 @default.
• W2554159443 hasConcept C2780474809 @default.

• next