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- W2554445187 endingPage "214" @default.
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- W2554445187 abstract "In this article, we review the past applications of in vitro models in identifying human hepatotoxins and then focus on the use of multiscale experimental models in drug development, including the use of zebrafish and human cell-based, 3-dimensional, microfluidic systems of liver functions as key components in applying Quantitative Systems Pharmacology (QSP). We have implemented QSP as a platform to improve the rate of success in the process of drug discovery and development of therapeutics." @default.
- W2554445187 created "2016-11-30" @default.
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- W2554445187 date "2017-02-01" @default.
- W2554445187 modified "2023-10-02" @default.
- W2554445187 title "Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy" @default.
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- W2554445187 doi "https://doi.org/10.1016/j.cld.2016.08.013" @default.
- W2554445187 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6325638" @default.
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