FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2554544102> ?p ?o ?g. }

• W2554544102 endingPage "59" @default.
• W2554544102 startingPage "50" @default.
• W2554544102 abstract "Oncovirus-associated malignancies are potentially preventable diseases with major public health significance. Human polyomaviruses (HPyVs) may be associated with oncogenesis or symptomatic illnesses in immunocompromised patients, but the site of viral shedding of most recently discovered HPyVs remains obscure. Using real-time PCR assay using specific primers targeting the HPyV6 large tumor antigen gene, we detected a phylogenetically distinct HPyV6 which was highly prevalent in the bile samples of patients with malignant biliary obstruction (18.8%) and acute gallstone cholangitis (5.5%). The prevalence rate and mean viral load of this HPyV6 were highest in the cholangiocarcinoma subgroup (27.6% and 2.41 × 104copies/ml). These findings were confirmed with another real-time PCR assay using specific primers targeting the HPyV6 viral capsid protein 2 gene. These bile HPyV6 strains may represent a novel clade of HPyV6 as they formed a distinct cluster from the other HPyV6s and exhibited >2% differences in amino acid sequences in their major proteins. While HPyV6 was unlikely the cause of the patients' acute symptoms and liver dysfunction, the virus may be related to immunosuppression in patients with malignancy and/or important in the oncogenesis of cholangiocarcinoma in patients without coinfection with other oncogenic microbes. Further studies to ascertain a causative role of HPyV6 in cholangiocarcinoma should be conducted." @default.
• W2554544102 created "2016-11-30" @default.
• W2554544102 creator A5013250705 @default.
• W2554544102 creator A5014473034 @default.
• W2554544102 creator A5021544416 @default.
• W2554544102 creator A5023114656 @default.
• W2554544102 creator A5030565867 @default.
• W2554544102 creator A5069122598 @default.
• W2554544102 creator A5073090269 @default.
• W2554544102 creator A5074667163 @default.
• W2554544102 creator A5074675036 @default.
• W2554544102 creator A5086034644 @default.
• W2554544102 date "2017-01-01" @default.
• W2554544102 modified "2023-10-14" @default.
• W2554544102 title "First detection and complete genome sequence of a phylogenetically distinct human polyomavirus 6 highly prevalent in human bile samples" @default.
• W2554544102 cites W1909380844 @default.
• W2554544102 cites W1968043542 @default.
• W2554544102 cites W1970651352 @default.
• W2554544102 cites W1974345074 @default.
• W2554544102 cites W1975533555 @default.
• W2554544102 cites W2001537500 @default.
• W2554544102 cites W2004533831 @default.
• W2554544102 cites W2004864553 @default.
• W2554544102 cites W2019934363 @default.
• W2554544102 cites W2048878373 @default.
• W2554544102 cites W2052437948 @default.
• W2554544102 cites W2060200661 @default.
• W2554544102 cites W2070256828 @default.
• W2554544102 cites W2070476769 @default.
• W2554544102 cites W2076157876 @default.
• W2554544102 cites W2077399661 @default.
• W2554544102 cites W2081529302 @default.
• W2554544102 cites W208272045 @default.
• W2554544102 cites W2085487956 @default.
• W2554544102 cites W2096076362 @default.
• W2554544102 cites W2103082445 @default.
• W2554544102 cites W2118913456 @default.
• W2554544102 cites W2122060603 @default.
• W2554544102 cites W2126340442 @default.
• W2554544102 cites W2133425928 @default.
• W2554544102 cites W2147963937 @default.
• W2554544102 cites W2152207030 @default.
• W2554544102 cites W2160851684 @default.
• W2554544102 cites W2160994473 @default.
• W2554544102 cites W2163631211 @default.
• W2554544102 cites W2182529209 @default.
• W2554544102 cites W2299248163 @default.
• W2554544102 cites W2304226292 @default.
• W2554544102 cites W2309526919 @default.
• W2554544102 cites W2339908029 @default.
• W2554544102 cites W2460607141 @default.
• W2554544102 cites W4211025847 @default.
• W2554544102 doi "https://doi.org/10.1016/j.jinf.2016.11.002" @default.
• W2554544102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27840269" @default.
• W2554544102 hasPublicationYear "2017" @default.
• W2554544102 type Work @default.
• W2554544102 sameAs 2554544102 @default.
• W2554544102 citedByCount "6" @default.
• W2554544102 countsByYear W25545441022017 @default.
• W2554544102 countsByYear W25545441022018 @default.
• W2554544102 countsByYear W25545441022019 @default.
• W2554544102 countsByYear W25545441022020 @default.
• W2554544102 countsByYear W25545441022021 @default.
• W2554544102 crossrefType "journal-article" @default.
• W2554544102 hasAuthorship W2554544102A5013250705 @default.
• W2554544102 hasAuthorship W2554544102A5014473034 @default.
• W2554544102 hasAuthorship W2554544102A5021544416 @default.
• W2554544102 hasAuthorship W2554544102A5023114656 @default.
• W2554544102 hasAuthorship W2554544102A5030565867 @default.
• W2554544102 hasAuthorship W2554544102A5069122598 @default.
• W2554544102 hasAuthorship W2554544102A5073090269 @default.
• W2554544102 hasAuthorship W2554544102A5074667163 @default.
• W2554544102 hasAuthorship W2554544102A5074675036 @default.
• W2554544102 hasAuthorship W2554544102A5086034644 @default.
• W2554544102 hasConcept C104317684 @default.
• W2554544102 hasConcept C159047783 @default.
• W2554544102 hasConcept C203014093 @default.
• W2554544102 hasConcept C2522874641 @default.
• W2554544102 hasConcept C2777072776 @default.
• W2554544102 hasConcept C2777813720 @default.
• W2554544102 hasConcept C2779399171 @default.
• W2554544102 hasConcept C2780252810 @default.
• W2554544102 hasConcept C54355233 @default.
• W2554544102 hasConcept C555283112 @default.
• W2554544102 hasConcept C86803240 @default.
• W2554544102 hasConceptScore W2554544102C104317684 @default.
• W2554544102 hasConceptScore W2554544102C159047783 @default.
• W2554544102 hasConceptScore W2554544102C203014093 @default.
• W2554544102 hasConceptScore W2554544102C2522874641 @default.
• W2554544102 hasConceptScore W2554544102C2777072776 @default.
• W2554544102 hasConceptScore W2554544102C2777813720 @default.
• W2554544102 hasConceptScore W2554544102C2779399171 @default.
• W2554544102 hasConceptScore W2554544102C2780252810 @default.
• W2554544102 hasConceptScore W2554544102C54355233 @default.
• W2554544102 hasConceptScore W2554544102C555283112 @default.
• W2554544102 hasConceptScore W2554544102C86803240 @default.
• W2554544102 hasIssue "1" @default.
• W2554544102 hasLocation W25545441021 @default.

• next