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- W2554718054 abstract "In the present work, an attempt has been made to develop fast disintegrating tablets of Telmisartan HCl. In the present work sodium Primogel,Polyplasdone XL and Vivasol were employed as super disintegrating agents to enhance the solubility and dissolution rate of selected drug molecule. Camphor was employed as sublimating agent, due to presence of camphor maximum pores will be formed. As the numbers of pores were more the body fluid will penetrates more easily. All the formulations were prepared by direct compression method using 8mm punch on 8 station rotary tablet punching machine. The blend of all the formulations showed god flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. Among all the formulations F9 formulation showed maximum % drug release i.e., 110.4 % in 2 min hence it is considered as optimized formulation. The F9 formulation contains Vivasol as super disintegrate in the concentration of 20 mg. Keywords: Telmisartan HCl , Sublimating agent , camphor, Primogel, Polyplasdone XL and Vivasol." @default.
- W2554718054 created "2016-11-30" @default.
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- W2554718054 date "2015-01-01" @default.
- W2554718054 modified "2023-09-24" @default.
- W2554718054 title "Formulation of Telmisartan HCL Fast Disintegrating Tablets by Sublimation Technique" @default.
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