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• W2555121231 startingPage "39" @default.
• W2555121231 abstract "Aspergillus species cause a range of respiratory diseases in humans. While immunocompromised patients are at risk for the development of invasive infection with these opportunistic molds, patients with underlying pulmonary disease can develop chronic airway infection with Aspergillus species. These conditions span a range of inflammatory and allergic diseases including Aspergillus bronchitis, allergic bronchopulmonary aspergillosis, and severe asthma with fungal sensitization. Animal models are invaluable tools for the study of the molecular mechanism underlying the colonization of airways by Aspergillus and the host response to these non-invasive infections. In this review we summarize the state-of-the-art with respect to the available animal models of noninvasive and allergic Aspergillus airway disease; the key findings of host-pathogen interaction studies using these models; and the limitations and future directions that should guide the development and use of models for the study of these important pulmonary conditions." @default.
• W2555121231 created "2016-11-30" @default.
• W2555121231 creator A5023246115 @default.
• W2555121231 creator A5025718032 @default.
• W2555121231 date "2016-11-12" @default.
• W2555121231 modified "2023-10-17" @default.
• W2555121231 title "<i>Aspergillus</i>in chronic lung disease: Modeling what goes on in the airways" @default.
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• W2555121231 doi "https://doi.org/10.1093/mmy/myw117" @default.
• W2555121231 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27838644" @default.
• W2555121231 hasPublicationYear "2016" @default.
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