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- W2555264953 abstract "An African-American man aged 65 years with multiple malignancies in remission was admitted for small bowel obstruction. He was treated with laparotomy following failure of conservative management. Postoperatively, he developed intra-abdominal bleed, which persisted, despite surgical haematoma evacuation. Further haematological workup revealed isolated prolongation of activated partial thromboplastin time (aPTT) with reduced factor VIII (FVIII) activity and raised FVIII inhibitor titre. Assuming acquired haemophilia A (AHA), FVIII inhibitor bypassing activity and corticosteroids were started with subsequent resolution of the bleeding from the surgical site. The patient remained free of bleeding episodes at 3-month follow-up and the aPTT normalised. This case report highlights the association of surgery with AHA and summarises the treatments with underlying mechanisms." @default.
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- W2555264953 date "2016-11-16" @default.
- W2555264953 modified "2023-09-26" @default.
- W2555264953 title "Acquired haemophilia A: an unusual postoperative complication" @default.
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- W2555264953 doi "https://doi.org/10.1136/bcr-2016-217198" @default.
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