FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2555374507> ?p ?o ?g. }

• W2555374507 endingPage "51" @default.
• W2555374507 startingPage "38" @default.
• W2555374507 abstract "Abstract. Local release of antibiotic has advantages in the treatment of chronic osteomyelitis and infected fractures. The adequacy of surgical debridement is still key to successful clearance of infection but local antibiotic carriers seem to afford greater success rates by targeting the residual organisms present after debridement and delivering much higher local antibiotic concentrations compared with systemic antibiotics alone. Biodegradable ceramic carriers can be used to fill osseous defects, which reduces the dead space and provides the potential for subsequent repair of the osseous defect as they dissolve away. A dissolving ceramic antibiotic carrier also raises the possibility of single stage surgery with definitive closure and avoids the need for subsequent surgery for spacer removal.In this article we provide an overview of the properties of various biodegradable ceramics, including calcium sulphate, the calcium orthophosphate ceramics, calcium phosphate cement and polyphasic carriers. We summarise the antibiotic elution properties as investigated in previous animal studies as well as the clinical outcomes from clinical research investigating their use in the surgical management of chronic osteomyelitis.Calcium sulphate pellets have been shown to be effective in treating local infection, although newer polyphasic carriers may support greater osseous repair and reduce the risk of further fracture or the need for secondary reconstructive surgery. The use of ceramic biocomposites to deliver antibiotics together with BMPs, bisphosphonates, growth factors or living cells is under investigation and merits further study.We propose a treatment protocol, based on the Cierny-Mader classification, to help guide the appropriate selection of a suitable ceramic antibiotic carrier in the surgical treatment of chronic osteomyelitis." @default.
• W2555374507 created "2016-11-30" @default.
• W2555374507 creator A5043072363 @default.
• W2555374507 creator A5045306498 @default.
• W2555374507 creator A5085215589 @default.
• W2555374507 date "2017-01-01" @default.
• W2555374507 modified "2023-10-06" @default.
• W2555374507 title "Ceramic Biocomposites as Biodegradable Antibiotic Carriers in the Treatment of Bone Infections" @default.
• W2555374507 cites W14869533 @default.
• W2555374507 cites W1502205002 @default.
• W2555374507 cites W1522404613 @default.
• W2555374507 cites W174364120 @default.
• W2555374507 cites W1855642336 @default.
• W2555374507 cites W18650605 @default.
• W2555374507 cites W1906639664 @default.
• W2555374507 cites W1967149655 @default.
• W2555374507 cites W1979457189 @default.
• W2555374507 cites W1985185488 @default.
• W2555374507 cites W1985441897 @default.
• W2555374507 cites W1992838633 @default.
• W2555374507 cites W1996176602 @default.
• W2555374507 cites W1996752928 @default.
• W2555374507 cites W1998484607 @default.
• W2555374507 cites W1998690761 @default.
• W2555374507 cites W1998727589 @default.
• W2555374507 cites W1999869481 @default.
• W2555374507 cites W2002965602 @default.
• W2555374507 cites W2004653800 @default.
• W2555374507 cites W2006960912 @default.
• W2555374507 cites W2008722836 @default.
• W2555374507 cites W2009147618 @default.
• W2555374507 cites W2009820479 @default.
• W2555374507 cites W2016582279 @default.
• W2555374507 cites W2016945026 @default.
• W2555374507 cites W2023287513 @default.
• W2555374507 cites W2037956183 @default.
• W2555374507 cites W2042963192 @default.
• W2555374507 cites W2046679094 @default.
• W2555374507 cites W2049393551 @default.
• W2555374507 cites W2063191538 @default.
• W2555374507 cites W2064409905 @default.
• W2555374507 cites W2066044675 @default.
• W2555374507 cites W2066247076 @default.
• W2555374507 cites W2072905377 @default.
• W2555374507 cites W2079536342 @default.
• W2555374507 cites W2087994768 @default.
• W2555374507 cites W2093826323 @default.
• W2555374507 cites W2093923848 @default.
• W2555374507 cites W2094562739 @default.
• W2555374507 cites W2100041521 @default.
• W2555374507 cites W2103338895 @default.
• W2555374507 cites W2109344577 @default.
• W2555374507 cites W2110803235 @default.
• W2555374507 cites W2111469399 @default.
• W2555374507 cites W2115811995 @default.
• W2555374507 cites W2121069945 @default.
• W2555374507 cites W2122951429 @default.
• W2555374507 cites W2125603952 @default.
• W2555374507 cites W2126329489 @default.
• W2555374507 cites W2140271695 @default.
• W2555374507 cites W2142057495 @default.
• W2555374507 cites W2144015007 @default.
• W2555374507 cites W2154358116 @default.
• W2555374507 cites W2155983200 @default.
• W2555374507 cites W2157903965 @default.
• W2555374507 cites W2163768016 @default.
• W2555374507 cites W2164343599 @default.
• W2555374507 cites W2167815042 @default.
• W2555374507 cites W2170163048 @default.
• W2555374507 cites W2202067380 @default.
• W2555374507 cites W2232383599 @default.
• W2555374507 cites W2265724476 @default.
• W2555374507 cites W2285214163 @default.
• W2555374507 cites W2293676967 @default.
• W2555374507 cites W2344252238 @default.
• W2555374507 cites W2396893196 @default.
• W2555374507 cites W2483759567 @default.
• W2555374507 cites W2509593593 @default.
• W2555374507 cites W2525938729 @default.
• W2555374507 cites W25570946 @default.
• W2555374507 cites W2605745936 @default.
• W2555374507 cites W4238526877 @default.
• W2555374507 cites W4249131922 @default.
• W2555374507 cites W4294253811 @default.
• W2555374507 cites W93021145 @default.
• W2555374507 doi "https://doi.org/10.7150/jbji.17234" @default.
• W2555374507 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5423569" @default.
• W2555374507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28529863" @default.
• W2555374507 hasPublicationYear "2017" @default.
• W2555374507 type Work @default.
• W2555374507 sameAs 2555374507 @default.
• W2555374507 citedByCount "104" @default.
• W2555374507 countsByYear W25553745072017 @default.
• W2555374507 countsByYear W25553745072018 @default.
• W2555374507 countsByYear W25553745072019 @default.
• W2555374507 countsByYear W25553745072020 @default.
• W2555374507 countsByYear W25553745072021 @default.
• W2555374507 countsByYear W25553745072022 @default.

• next