Matches in SemOpenAlex for { <https://semopenalex.org/work/W2555558129> ?p ?o ?g. }
- W2555558129 abstract "The ascending thoracic aorta is poorly understood mechanically, especially its risk of dissection. To make better predictions of dissection risk, more information about the multidimensional failure behavior of the tissue is needed, and this information must be incorporated into an appropriate theoretical/computational model. Toward the creation of such a model, uniaxial, equibiaxial, peel, and shear lap tests were performed on healthy porcine ascending aorta samples. Uniaxial and equibiaxial tests showed anisotropy with greater stiffness and strength in the circumferential direction. Shear lap tests showed catastrophic failure at shear stresses (150–200 kPa) much lower than uniaxial tests (750–2500 kPa), consistent with the low peel tension (∼60 mN/mm). A novel multiscale computational model, including both prefailure and failure mechanics of the aorta, was developed. The microstructural part of the model included contributions from a collagen-reinforced elastin sheet and interlamellar connections representing fibrillin and smooth muscle. Components were represented as nonlinear fibers that failed at a critical stretch. Multiscale simulations of the different experiments were performed, and the model, appropriately specified, agreed well with all experimental data, representing a uniquely complete structure-based description of aorta mechanics. In addition, our experiments and model demonstrate the very low strength of the aorta in radial shear, suggesting an important possible mechanism for aortic dissection." @default.
- W2555558129 created "2016-11-30" @default.
- W2555558129 creator A5000471565 @default.
- W2555558129 creator A5009817534 @default.
- W2555558129 creator A5013483780 @default.
- W2555558129 creator A5020019949 @default.
- W2555558129 creator A5052683196 @default.
- W2555558129 creator A5062712899 @default.
- W2555558129 creator A5066370695 @default.
- W2555558129 date "2017-01-23" @default.
- W2555558129 modified "2023-10-18" @default.
- W2555558129 title "Failure of the Porcine Ascending Aorta: Multidirectional Experiments and a Unifying Microstructural Model" @default.
- W2555558129 cites W1493786307 @default.
- W2555558129 cites W151897849 @default.
- W2555558129 cites W1569437667 @default.
- W2555558129 cites W1779733076 @default.
- W2555558129 cites W1827569473 @default.
- W2555558129 cites W1945277511 @default.
- W2555558129 cites W1963977555 @default.
- W2555558129 cites W1966271582 @default.
- W2555558129 cites W1966795228 @default.
- W2555558129 cites W1966970487 @default.
- W2555558129 cites W1974961631 @default.
- W2555558129 cites W1977348040 @default.
- W2555558129 cites W1977377552 @default.
- W2555558129 cites W1983280624 @default.
- W2555558129 cites W1983991540 @default.
- W2555558129 cites W1991383279 @default.
- W2555558129 cites W1996901223 @default.
- W2555558129 cites W2000333410 @default.
- W2555558129 cites W2011247521 @default.
- W2555558129 cites W2017327254 @default.
- W2555558129 cites W2018090500 @default.
- W2555558129 cites W2027493693 @default.
- W2555558129 cites W2029081117 @default.
- W2555558129 cites W2029653395 @default.
- W2555558129 cites W2035779428 @default.
- W2555558129 cites W2036422131 @default.
- W2555558129 cites W2040068690 @default.
- W2555558129 cites W2041009444 @default.
- W2555558129 cites W2044837181 @default.
- W2555558129 cites W2046509297 @default.
- W2555558129 cites W2046843227 @default.
- W2555558129 cites W2048339072 @default.
- W2555558129 cites W2049119880 @default.
- W2555558129 cites W2050001975 @default.
- W2555558129 cites W2054741552 @default.
- W2555558129 cites W2060548739 @default.
- W2555558129 cites W2067891684 @default.
- W2555558129 cites W2068778098 @default.
- W2555558129 cites W2076416315 @default.
- W2555558129 cites W2079818208 @default.
- W2555558129 cites W2081189235 @default.
- W2555558129 cites W2093860004 @default.
- W2555558129 cites W2094047922 @default.
- W2555558129 cites W2099593084 @default.
- W2555558129 cites W2100139763 @default.
- W2555558129 cites W2105727222 @default.
- W2555558129 cites W2105967135 @default.
- W2555558129 cites W2112123157 @default.
- W2555558129 cites W2112718906 @default.
- W2555558129 cites W2125071760 @default.
- W2555558129 cites W2125419946 @default.
- W2555558129 cites W2130081638 @default.
- W2555558129 cites W2132831536 @default.
- W2555558129 cites W2133020498 @default.
- W2555558129 cites W2137408743 @default.
- W2555558129 cites W2146052423 @default.
- W2555558129 cites W2148219688 @default.
- W2555558129 cites W2150838305 @default.
- W2555558129 cites W2151037755 @default.
- W2555558129 cites W2153748516 @default.
- W2555558129 cites W2154844668 @default.
- W2555558129 cites W2155257926 @default.
- W2555558129 cites W2159994931 @default.
- W2555558129 cites W2161661378 @default.
- W2555558129 cites W2182344402 @default.
- W2555558129 cites W2283203780 @default.
- W2555558129 cites W2412118497 @default.
- W2555558129 cites W35627585 @default.
- W2555558129 doi "https://doi.org/10.1115/1.4035264" @default.
- W2555558129 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5395918" @default.
- W2555558129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27893044" @default.
- W2555558129 hasPublicationYear "2017" @default.
- W2555558129 type Work @default.
- W2555558129 sameAs 2555558129 @default.
- W2555558129 citedByCount "39" @default.
- W2555558129 countsByYear W25555581292017 @default.
- W2555558129 countsByYear W25555581292018 @default.
- W2555558129 countsByYear W25555581292019 @default.
- W2555558129 countsByYear W25555581292020 @default.
- W2555558129 countsByYear W25555581292021 @default.
- W2555558129 countsByYear W25555581292022 @default.
- W2555558129 countsByYear W25555581292023 @default.
- W2555558129 crossrefType "journal-article" @default.
- W2555558129 hasAuthorship W2555558129A5000471565 @default.
- W2555558129 hasAuthorship W2555558129A5009817534 @default.
- W2555558129 hasAuthorship W2555558129A5013483780 @default.
- W2555558129 hasAuthorship W2555558129A5020019949 @default.
- W2555558129 hasAuthorship W2555558129A5052683196 @default.