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• W2555631370 abstract "Summary Introduction. Medial temporal lobe epilepsy (MTLE) is the most frequent form of epilepsy in adulthood. It is classified as local/regional epilepsy. However, there is increasing evidence of the involvement of both temporal lobes and this provides abundant arguments to question this view, and consider MTLE as one of the typical bilateral system epilepsies. Aim. To provide a contemporary review of medial temporal lobe epilepsy, discussing the bilateral aspects, with reference to epilepsy surgery. Methods. A literature review and a resume of the author’s own experiences with MTLE patients. Results. Recent electrophysiological and neuroimaging data provide convincing data supporting that MTLE is a bilateral disease. The uni-and bilateral features form a continuum and the participation rate of the two temporal lobes determine course and surgical perspective of the individual patient. Conclusions. The contradictory data of invasive presurgical evaluations of MTLE patients suggest that there need to identify further indicatory markers of bilaterality and thus change the presurgical evaluation from the non-invasive towards the invasive ways. The mechanisms of the interrelationship between the two temporal lobes in MTLE warrants further research." @default.
• W2555631370 created "2016-11-30" @default.
• W2555631370 creator A5001231385 @default.
• W2555631370 date "2016-12-01" @default.
• W2555631370 modified "2023-10-13" @default.
• W2555631370 title "The medial temporal lobe epilepsy is a bilateral disease – novel aspects" @default.
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• W2555631370 doi "https://doi.org/10.1515/joepi-2016-0010" @default.
• W2555631370 hasPublicationYear "2016" @default.
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