Matches in SemOpenAlex for { <https://semopenalex.org/work/W2555642015> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2555642015 abstract "Lung cancer is the leading cause of cancer death. The endothelin-1 (EDN1)/endothelin A receptor (EDNRA) axis may directly contribute to tumor growth and indirectly modulate tumor–host interactions in various tumors. Since the genetic background between EDN1/EDNRA and non-small cell lung cancer (NSCLC) remains unknown. In this study, the association of genotypic polymorphisms in EDN1 and EDNRA with NSCLC was investigated. 388 patients with NSCLC and 396 healthy controls recruited from the China Medical Hospital in Taiwan were genotyped by a PCR-RFLP method. Results: Overall, the distribution of the genotype frequencies of EDN1 rs5370 G/T and EDNRA rs5333 T/C were significantly different between the lung cancer patients and the healthy controls, and also different between patients with lung cancers of various stages. Logistic regression analysis revealed that higher odds ratios (ORs) for lung cancer were seen for individuals with EDN1 rs5370 TT genotype against GG/GT genotypes (an OR of 4.22, 95% CI 2.68-7.02, p Conclusions: A significant association between the EDN1 rs5370 G/T and EDNRA rs5333 T/C genetic polymorphisms and the susceptibility to NSCLC was demonstrated. Also, these two polymorphisms were associated with the severity of lung cancer. The EDN1 rs5370 TT and EDNRA rs5333 CC genotypes have a promotive effect for lung cancer development and progression." @default.
- W2555642015 created "2016-11-30" @default.
- W2555642015 creator A5070887714 @default.
- W2555642015 creator A5081792610 @default.
- W2555642015 date "2016-09-01" @default.
- W2555642015 modified "2023-09-23" @default.
- W2555642015 title "Association of the endothelin-1 and endothelin A receptor genetic polymorphisms and non-small cell lung cancer in Taiwan" @default.
- W2555642015 doi "https://doi.org/10.1183/13993003.congress-2016.pa2856" @default.
- W2555642015 hasPublicationYear "2016" @default.
- W2555642015 type Work @default.
- W2555642015 sameAs 2555642015 @default.
- W2555642015 citedByCount "0" @default.
- W2555642015 crossrefType "proceedings-article" @default.
- W2555642015 hasAuthorship W2555642015A5070887714 @default.
- W2555642015 hasAuthorship W2555642015A5081792610 @default.
- W2555642015 hasConcept C104317684 @default.
- W2555642015 hasConcept C126322002 @default.
- W2555642015 hasConcept C135763542 @default.
- W2555642015 hasConcept C143998085 @default.
- W2555642015 hasConcept C144980905 @default.
- W2555642015 hasConcept C149601957 @default.
- W2555642015 hasConcept C151956035 @default.
- W2555642015 hasConcept C156957248 @default.
- W2555642015 hasConcept C170493617 @default.
- W2555642015 hasConcept C203014093 @default.
- W2555642015 hasConcept C2776256026 @default.
- W2555642015 hasConcept C2777714996 @default.
- W2555642015 hasConcept C54355233 @default.
- W2555642015 hasConcept C71924100 @default.
- W2555642015 hasConcept C86803240 @default.
- W2555642015 hasConceptScore W2555642015C104317684 @default.
- W2555642015 hasConceptScore W2555642015C126322002 @default.
- W2555642015 hasConceptScore W2555642015C135763542 @default.
- W2555642015 hasConceptScore W2555642015C143998085 @default.
- W2555642015 hasConceptScore W2555642015C144980905 @default.
- W2555642015 hasConceptScore W2555642015C149601957 @default.
- W2555642015 hasConceptScore W2555642015C151956035 @default.
- W2555642015 hasConceptScore W2555642015C156957248 @default.
- W2555642015 hasConceptScore W2555642015C170493617 @default.
- W2555642015 hasConceptScore W2555642015C203014093 @default.
- W2555642015 hasConceptScore W2555642015C2776256026 @default.
- W2555642015 hasConceptScore W2555642015C2777714996 @default.
- W2555642015 hasConceptScore W2555642015C54355233 @default.
- W2555642015 hasConceptScore W2555642015C71924100 @default.
- W2555642015 hasConceptScore W2555642015C86803240 @default.
- W2555642015 hasLocation W25556420151 @default.
- W2555642015 hasOpenAccess W2555642015 @default.
- W2555642015 hasPrimaryLocation W25556420151 @default.
- W2555642015 hasRelatedWork W184899741 @default.
- W2555642015 hasRelatedWork W1977479344 @default.
- W2555642015 hasRelatedWork W2159469480 @default.
- W2555642015 hasRelatedWork W2238280291 @default.
- W2555642015 hasRelatedWork W2250554689 @default.
- W2555642015 hasRelatedWork W2332713365 @default.
- W2555642015 hasRelatedWork W2342562372 @default.
- W2555642015 hasRelatedWork W2405287372 @default.
- W2555642015 hasRelatedWork W2796262101 @default.
- W2555642015 hasRelatedWork W2884724486 @default.
- W2555642015 hasRelatedWork W2899850867 @default.
- W2555642015 hasRelatedWork W2900417429 @default.
- W2555642015 hasRelatedWork W2912603490 @default.
- W2555642015 hasRelatedWork W2924341319 @default.
- W2555642015 hasRelatedWork W2950538959 @default.
- W2555642015 hasRelatedWork W2972594668 @default.
- W2555642015 hasRelatedWork W2988438386 @default.
- W2555642015 hasRelatedWork W3000300814 @default.
- W2555642015 hasRelatedWork W3029772354 @default.
- W2555642015 hasRelatedWork W3109662599 @default.
- W2555642015 isParatext "false" @default.
- W2555642015 isRetracted "false" @default.
- W2555642015 magId "2555642015" @default.
- W2555642015 workType "article" @default.