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- W2555761488 abstract "CIs stimulate the auditory nerve fibers (ANF) with a train of amplitude modulated current pulses. Depending on polarity, the pulses can generate spikes at different sites along the ANF. The latency difference between spikes generated at the central and the peripheral axons was found to be up to 200 μs in cats and up to 450 μs in humans. These timing differences could be the reason underlying the poor performance of CI listeners in ITD perception. A model of ANF responses to electrical stimulation (Joshi et al., 2016), which includes two sites of spike generation along the ANF was used to simulate the ANF responses to constant-amplitude and modulated pulse trains for different pulse-rates. The fidelity of the temporal coding was quantified by calculating the phase-locking value. The results show that an increase in pulse-rate leads to higher uncertainty in the site of spike generation, reduction in phase-locking, and increase in variance of its distribution. This may account for impaired ITD thresholds observed at high pulse-rates. The simulated monaural spike trains are then used predict the ITD discrimination thresholds by imposing delays between the two pulse trains and to identify the factors that affect ITD coding in CI listeners." @default.
- W2555761488 created "2016-11-30" @default.
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- W2555761488 date "2016-10-01" @default.
- W2555761488 modified "2023-09-27" @default.
- W2555761488 title "Modelling the effect of pulse-rate on coding of interaural time differences in listeners with cochlear implants" @default.
- W2555761488 doi "https://doi.org/10.1121/1.4970392" @default.
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