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- W2555847216 abstract "Purpose: To investigate the effects of combined jumping exercise and honey supplementation on bone metabolism and antioxidant status in female rats. Methods: Forty eight 12-week old Sprague Dawley female rats were divided into four groups: control group (C), honey group (H), jumping group (J), and combined jumping and honey group (JH). Jumping exercise consisted of 40 jumps/day for 5 days/week at a height of 40 cm. Honey was given to the rats at a dosage of 1 g/kg body weight/rat/day via force feeding for 7 days/week. At the end of the study, tibial proximal volumetric total Bone Mineral Density (BMD) and volumetric trabecular BMD, serum total calcium, serum Alkaline Phosphatase (ALP) (bone formation marker), serum C-terminal telopeptide of type 1 procollagen (1CTP) (bone resorption marker), serum F 2 -isoprostanes (oxidative stress marker) and serum Total Antioxidant Status (TAS) were measured. Results: There were no significant differences in tibial proximal volumetric total BMD and volumetric trabecular BMD among all the groups. Eight weeks of jumping exercise and honey supplementation resulted in statistically significant higher serum total calcium concentration in JH group as compared to C, H and J groups (p < 0.05). Serum ALP was significantly higher in J group as compared to C group (p < 0.05). On the other hand, serum 1CTP was significantly lower in JH as compared to the other three experimental groups. The concentration of F2-isoprostanes was not statistically different among all the groups. Serum TAS was significantly higher in JH and H groups as compared to C group (p < 0.05) respectively. Conclusion: The results of the present study showed that 8 weeks of jumping exercise and honey supplementation significantly reduced bone resorption and enhanced antioxidant status, but did not seem to elevate oxidative stress marker." @default.
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- W2555847216 date "2015-01-15" @default.
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- W2555847216 title "Changes in Bone Metabolism and Antioxidant Status with Combined Exercise and Honey Supplementation in Young Female Rats" @default.
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- W2555847216 doi "https://doi.org/10.15226/2374-6904/2/2/00127" @default.
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