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• W2555875659 abstract "A new global post-translational modification (PTM) discovery strategy, G-PTM-D, is described. A proteomics database containing UniProt-curated PTM information is supplemented with potential new modification types and sites discovered from a first-round search of mass spectrometry data with ultrawide precursor mass tolerance. A second-round search employing the supplemented database conducted with standard narrow mass tolerances yields deep coverage and a rich variety of peptide modifications with high confidence in complex unenriched samples. The G-PTM-D strategy represents a major advance to the previously reported G-PTM strategy and provides a powerful new capability to the proteomics research community." @default.
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• W2555875659 date "2017-03-01" @default.
• W2555875659 modified "2023-10-17" @default.
• W2555875659 title "Global Post-Translational Modification Discovery" @default.
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• W2555875659 doi "https://doi.org/10.1021/acs.jproteome.6b00034" @default.
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