FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2555994544> ?p ?o ?g. }

• W2555994544 endingPage "1888" @default.
• W2555994544 startingPage "1888" @default.
• W2555994544 abstract "Allergic asthma is an inflammatory lung disease that is partly sustained by the chemokine eotaxin-3 (CCL26), which extends eosinophil migration into tissues long after allergen exposure. Modulation of CCL26 could represent a means to mitigate airway inflammation. Here we evaluated procyanidin A2 as a means of modulating CCL26 production and investigated interactions with the known inflammation modulator, Interferon γ (IFNγ). We used the human lung epithelial cell line A549 and optimized the conditions for inducing CCL26. Cells were exposed to a range of procyanidin A2 or IFNγ concentrations for varied lengths of time prior to an inflammatory insult of interleukin-4 (IL-4) for 24 h. An enzyme-linked immunosorbent assay was used to measure CCL26 production. Exposing cells to 5 μM procyanidin A2 (prior to IL-4) reduced CCL26 production by 35% compared with control. Greatest inhibition by procyanidin A2 was seen with a 2 h exposure prior to IL-4, whereas IFNγ inhibition was greatest at 24 h. Concomitant incubation of procyanidin A2 and IFNγ did not extend the inhibitory efficacy of procyanidin A2. These data provide evidence that procyanidin A2 can modulate IL-4-induced CCL26 production by A549 lung epithelial cells and that it does so in a manner that is different from IFNγ." @default.
• W2555994544 created "2016-11-30" @default.
• W2555994544 creator A5005984727 @default.
• W2555994544 creator A5018200032 @default.
• W2555994544 creator A5038709097 @default.
• W2555994544 creator A5042247935 @default.
• W2555994544 date "2016-11-12" @default.
• W2555994544 modified "2023-09-25" @default.
• W2555994544 title "Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells" @default.
• W2555994544 cites W1844440003 @default.
• W2555994544 cites W1931359360 @default.
• W2555994544 cites W1966365711 @default.
• W2555994544 cites W1989265564 @default.
• W2555994544 cites W1989698859 @default.
• W2555994544 cites W2006926075 @default.
• W2555994544 cites W2014196070 @default.
• W2555994544 cites W2015166493 @default.
• W2555994544 cites W2025140256 @default.
• W2555994544 cites W2027033796 @default.
• W2555994544 cites W2032427717 @default.
• W2555994544 cites W2034766225 @default.
• W2555994544 cites W2040068698 @default.
• W2555994544 cites W2040334938 @default.
• W2555994544 cites W2054334194 @default.
• W2555994544 cites W2055226402 @default.
• W2555994544 cites W2055351127 @default.
• W2555994544 cites W2055620043 @default.
• W2555994544 cites W2059315552 @default.
• W2555994544 cites W2062118639 @default.
• W2555994544 cites W2080083579 @default.
• W2555994544 cites W2085822581 @default.
• W2555994544 cites W2086959952 @default.
• W2555994544 cites W2096879742 @default.
• W2555994544 cites W2108302236 @default.
• W2555994544 cites W2117582728 @default.
• W2555994544 cites W2121763901 @default.
• W2555994544 cites W2135871391 @default.
• W2555994544 cites W2142623432 @default.
• W2555994544 cites W2148026781 @default.
• W2555994544 cites W2149475331 @default.
• W2555994544 cites W2152241963 @default.
• W2555994544 cites W2152418453 @default.
• W2555994544 cites W2156916681 @default.
• W2555994544 cites W2160287057 @default.
• W2555994544 cites W2168556140 @default.
• W2555994544 cites W2340799345 @default.
• W2555994544 cites W2511587052 @default.
• W2555994544 doi "https://doi.org/10.3390/ijms17111888" @default.
• W2555994544 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5133887" @default.
• W2555994544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27845745" @default.
• W2555994544 hasPublicationYear "2016" @default.
• W2555994544 type Work @default.
• W2555994544 sameAs 2555994544 @default.
• W2555994544 citedByCount "23" @default.
• W2555994544 countsByYear W25559945442016 @default.
• W2555994544 countsByYear W25559945442017 @default.
• W2555994544 countsByYear W25559945442018 @default.
• W2555994544 countsByYear W25559945442019 @default.
• W2555994544 countsByYear W25559945442020 @default.
• W2555994544 countsByYear W25559945442021 @default.
• W2555994544 countsByYear W25559945442022 @default.
• W2555994544 countsByYear W25559945442023 @default.
• W2555994544 crossrefType "journal-article" @default.
• W2555994544 hasAuthorship W2555994544A5005984727 @default.
• W2555994544 hasAuthorship W2555994544A5018200032 @default.
• W2555994544 hasAuthorship W2555994544A5038709097 @default.
• W2555994544 hasAuthorship W2555994544A5042247935 @default.
• W2555994544 hasBestOaLocation W25559945441 @default.
• W2555994544 hasConcept C185592680 @default.
• W2555994544 hasConcept C203014093 @default.
• W2555994544 hasConcept C2776042228 @default.
• W2555994544 hasConcept C2776914184 @default.
• W2555994544 hasConcept C2777037409 @default.
• W2555994544 hasConcept C86803240 @default.
• W2555994544 hasConceptScore W2555994544C185592680 @default.
• W2555994544 hasConceptScore W2555994544C203014093 @default.
• W2555994544 hasConceptScore W2555994544C2776042228 @default.
• W2555994544 hasConceptScore W2555994544C2776914184 @default.
• W2555994544 hasConceptScore W2555994544C2777037409 @default.
• W2555994544 hasConceptScore W2555994544C86803240 @default.
• W2555994544 hasIssue "11" @default.
• W2555994544 hasLocation W25559945441 @default.
• W2555994544 hasLocation W25559945442 @default.
• W2555994544 hasLocation W25559945443 @default.
• W2555994544 hasLocation W25559945444 @default.
• W2555994544 hasLocation W25559945445 @default.
• W2555994544 hasOpenAccess W2555994544 @default.
• W2555994544 hasPrimaryLocation W25559945441 @default.
• W2555994544 hasRelatedWork W1989249086 @default.
• W2555994544 hasRelatedWork W2000763162 @default.
• W2555994544 hasRelatedWork W2046818609 @default.
• W2555994544 hasRelatedWork W2047305992 @default.
• W2555994544 hasRelatedWork W2073100615 @default.
• W2555994544 hasRelatedWork W2083087446 @default.
• W2555994544 hasRelatedWork W2135474267 @default.
• W2555994544 hasRelatedWork W2409367678 @default.
• W2555994544 hasRelatedWork W3174744122 @default.
• W2555994544 hasRelatedWork W2188500368 @default.

• next