Matches in SemOpenAlex for { <https://semopenalex.org/work/W2556153007> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2556153007 abstract "<b>Background:</b> Previous prediction models for assessing risk of undiagnosed COPD used data from routine diagnoses, which may be inaccurate because of under- and misdiagnosis. We developed and externally validated a primary care-based model using data from a unique case finding trial. <b>Methods:</b> Patients aged 40-79 years with no prior diagnosis of COPD received a screening questionnaire either by post or opportunistically at primary care attendances through a large case finding trial based in primary care in the West Midlands, UK. Those reporting chronic respiratory symptoms were assessed with spirometry. COPD was defined as presence of respiratory symptoms and post-bronchodilator FEV<sub>1</sub>/FVC<lower limit of normal. A prediction model was developed using logistic regression with predictor variables available from electronic health records from subjects who returned a postal questionnaire (n=2398, mean age 59.9 years, 52% male). The model was externally validated among subjects who returned an opportunistic questionnaire (n=1097). <b>Results:</b> A model containing age, smoking status, dyspnoea, and prescriptions of salbutamol and antibiotics discriminated between patients with and without undiagnosed COPD (validation c-statistic 0.74 [95% CI 0.68 to 0.80]). A cut-point of ≥7.5% predicted risk to prompt referral for diagnostic assessment had a sensitivity of 68.8% (95% CI 57.3 to 78.9%) and specificity of 68.8% (95% CI 65.8.1 to 71.6%), requiring 7 diagnostic assessments (95% CI 6 to 10) to identify 1 patient with undiagnosed COPD. <b>Conclusion:</b> We have developed and externally validated a readily applicable risk model for undiagnosed COPD using routine data from electronic health records in primary care." @default.
- W2556153007 created "2016-11-30" @default.
- W2556153007 creator A5003740694 @default.
- W2556153007 creator A5011124689 @default.
- W2556153007 creator A5041409126 @default.
- W2556153007 creator A5059773134 @default.
- W2556153007 creator A5071393935 @default.
- W2556153007 creator A5076980555 @default.
- W2556153007 date "2016-09-01" @default.
- W2556153007 modified "2023-10-06" @default.
- W2556153007 title "Predicting risk of undiagnosed COPD in primary care: Development and validation of the TargetCOPD model" @default.
- W2556153007 doi "https://doi.org/10.1183/13993003.congress-2016.pa3930" @default.
- W2556153007 hasPublicationYear "2016" @default.
- W2556153007 type Work @default.
- W2556153007 sameAs 2556153007 @default.
- W2556153007 citedByCount "0" @default.
- W2556153007 crossrefType "proceedings-article" @default.
- W2556153007 hasAuthorship W2556153007A5003740694 @default.
- W2556153007 hasAuthorship W2556153007A5011124689 @default.
- W2556153007 hasAuthorship W2556153007A5041409126 @default.
- W2556153007 hasAuthorship W2556153007A5059773134 @default.
- W2556153007 hasAuthorship W2556153007A5071393935 @default.
- W2556153007 hasAuthorship W2556153007A5076980555 @default.
- W2556153007 hasBestOaLocation W25561530072 @default.
- W2556153007 hasConcept C126322002 @default.
- W2556153007 hasConcept C142724271 @default.
- W2556153007 hasConcept C151956035 @default.
- W2556153007 hasConcept C1862650 @default.
- W2556153007 hasConcept C187212893 @default.
- W2556153007 hasConcept C194828623 @default.
- W2556153007 hasConcept C2426938 @default.
- W2556153007 hasConcept C2776042228 @default.
- W2556153007 hasConcept C2776135927 @default.
- W2556153007 hasConcept C2776780178 @default.
- W2556153007 hasConcept C2780333948 @default.
- W2556153007 hasConcept C2984752397 @default.
- W2556153007 hasConcept C512399662 @default.
- W2556153007 hasConcept C534262118 @default.
- W2556153007 hasConcept C71924100 @default.
- W2556153007 hasConcept C98274493 @default.
- W2556153007 hasConceptScore W2556153007C126322002 @default.
- W2556153007 hasConceptScore W2556153007C142724271 @default.
- W2556153007 hasConceptScore W2556153007C151956035 @default.
- W2556153007 hasConceptScore W2556153007C1862650 @default.
- W2556153007 hasConceptScore W2556153007C187212893 @default.
- W2556153007 hasConceptScore W2556153007C194828623 @default.
- W2556153007 hasConceptScore W2556153007C2426938 @default.
- W2556153007 hasConceptScore W2556153007C2776042228 @default.
- W2556153007 hasConceptScore W2556153007C2776135927 @default.
- W2556153007 hasConceptScore W2556153007C2776780178 @default.
- W2556153007 hasConceptScore W2556153007C2780333948 @default.
- W2556153007 hasConceptScore W2556153007C2984752397 @default.
- W2556153007 hasConceptScore W2556153007C512399662 @default.
- W2556153007 hasConceptScore W2556153007C534262118 @default.
- W2556153007 hasConceptScore W2556153007C71924100 @default.
- W2556153007 hasConceptScore W2556153007C98274493 @default.
- W2556153007 hasLocation W25561530071 @default.
- W2556153007 hasLocation W25561530072 @default.
- W2556153007 hasOpenAccess W2556153007 @default.
- W2556153007 hasPrimaryLocation W25561530071 @default.
- W2556153007 hasRelatedWork W1848955419 @default.
- W2556153007 hasRelatedWork W1982233712 @default.
- W2556153007 hasRelatedWork W2015028963 @default.
- W2556153007 hasRelatedWork W2048952269 @default.
- W2556153007 hasRelatedWork W2094095485 @default.
- W2556153007 hasRelatedWork W2166326492 @default.
- W2556153007 hasRelatedWork W2201472204 @default.
- W2556153007 hasRelatedWork W2215595279 @default.
- W2556153007 hasRelatedWork W3036202486 @default.
- W2556153007 hasRelatedWork W4230865598 @default.
- W2556153007 isParatext "false" @default.
- W2556153007 isRetracted "false" @default.
- W2556153007 magId "2556153007" @default.
- W2556153007 workType "article" @default.