FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2556223824> ?p ?o ?g. }

• W2556223824 endingPage "8" @default.
• W2556223824 startingPage "1" @default.
• W2556223824 abstract "The initial characterisation of both mouse and human T cells described distinct and sharply defined cytokine patterns that were relatively stable and were functionally specialised for successfully attacking different pathogens. Additional phenotypes were then described, extending the range of functional types. However, more recently there have been many reports of further changes in cytokine patterns, and it is clear that all the recognised phenotypes were more plastic than originally thought. In particular, many intermediates between established subsets have been reported, for example Th1/Th17 cells expressing both IFNγ (interferon-gamma) and IL (interleukin)-17. This plasticity provides extra versatility for the immune system to adapt to changing infections and to altered requirements in different locations. A model of stochastic differentiation is presented, to visualise potential differentiation modes in the framework of a landscape model and to try to encourage discussion and experimentation regarding different mechanisms for plasticity. Key Concepts Initial models of highly stable T-cell subsets were useful but underestimated diversity. Flexibility is overlaid on partial stability. Many intermediate phenotypes can be induced. Several questions remain regarding temporary versus long-term plasticity alterations. Models for visualising differentiation need to be modified to include flexibility around a theme. Incorporation of stochastic trends may give a more useful representation of differentiation." @default.
• W2556223824 created "2016-11-30" @default.
• W2556223824 creator A5078753422 @default.
• W2556223824 creator A5081875590 @default.
• W2556223824 date "2016-11-15" @default.
• W2556223824 modified "2023-09-30" @default.
• W2556223824 title "<scp>T</scp>Lymphocytes: Plasticity of Subsets" @default.
• W2556223824 cites W1526621387 @default.
• W2556223824 cites W1571629216 @default.
• W2556223824 cites W1572743872 @default.
• W2556223824 cites W1599075296 @default.
• W2556223824 cites W1670334165 @default.
• W2556223824 cites W1827430542 @default.
• W2556223824 cites W1856738731 @default.
• W2556223824 cites W1942668068 @default.
• W2556223824 cites W1966226308 @default.
• W2556223824 cites W1972831560 @default.
• W2556223824 cites W1973408564 @default.
• W2556223824 cites W1980386568 @default.
• W2556223824 cites W1981480494 @default.
• W2556223824 cites W1982180094 @default.
• W2556223824 cites W1991323622 @default.
• W2556223824 cites W1996676269 @default.
• W2556223824 cites W1998047654 @default.
• W2556223824 cites W1998890676 @default.
• W2556223824 cites W2005246059 @default.
• W2556223824 cites W2006249161 @default.
• W2556223824 cites W2011736381 @default.
• W2556223824 cites W2011882192 @default.
• W2556223824 cites W2015976208 @default.
• W2556223824 cites W2021340905 @default.
• W2556223824 cites W2027699534 @default.
• W2556223824 cites W2028618405 @default.
• W2556223824 cites W2041765961 @default.
• W2556223824 cites W2045763435 @default.
• W2556223824 cites W2052873213 @default.
• W2556223824 cites W2054627147 @default.
• W2556223824 cites W2082450021 @default.
• W2556223824 cites W2082871926 @default.
• W2556223824 cites W2086221877 @default.
• W2556223824 cites W2086613600 @default.
• W2556223824 cites W2092837007 @default.
• W2556223824 cites W2095351296 @default.
• W2556223824 cites W2104112797 @default.
• W2556223824 cites W2111246573 @default.
• W2556223824 cites W2112133235 @default.
• W2556223824 cites W2114258661 @default.
• W2556223824 cites W2119636028 @default.
• W2556223824 cites W2120012263 @default.
• W2556223824 cites W2122939321 @default.
• W2556223824 cites W2123166427 @default.
• W2556223824 cites W2127278205 @default.
• W2556223824 cites W2129302556 @default.
• W2556223824 cites W2134717682 @default.
• W2556223824 cites W2136783271 @default.
• W2556223824 cites W2139565733 @default.
• W2556223824 cites W2148146593 @default.
• W2556223824 cites W2148720480 @default.
• W2556223824 cites W2151962109 @default.
• W2556223824 cites W2158882856 @default.
• W2556223824 cites W2159291439 @default.
• W2556223824 cites W2211069246 @default.
• W2556223824 cites W2284327277 @default.
• W2556223824 cites W2784110492 @default.
• W2556223824 cites W4313310226 @default.
• W2556223824 doi "https://doi.org/10.1002/9780470015902.a0026253" @default.
• W2556223824 hasPublicationYear "2016" @default.
• W2556223824 type Work @default.
• W2556223824 sameAs 2556223824 @default.
• W2556223824 citedByCount "0" @default.
• W2556223824 crossrefType "other" @default.
• W2556223824 hasAuthorship W2556223824A5078753422 @default.
• W2556223824 hasAuthorship W2556223824A5081875590 @default.
• W2556223824 hasConcept C104317684 @default.
• W2556223824 hasConcept C105795698 @default.
• W2556223824 hasConcept C112972136 @default.
• W2556223824 hasConcept C119857082 @default.
• W2556223824 hasConcept C121332964 @default.
• W2556223824 hasConcept C127716648 @default.
• W2556223824 hasConcept C169760540 @default.
• W2556223824 hasConcept C17744445 @default.
• W2556223824 hasConcept C18903297 @default.
• W2556223824 hasConcept C199539241 @default.
• W2556223824 hasConcept C203014093 @default.
• W2556223824 hasConcept C2776359362 @default.
• W2556223824 hasConcept C2778690821 @default.
• W2556223824 hasConcept C2780598303 @default.
• W2556223824 hasConcept C33923547 @default.
• W2556223824 hasConcept C41008148 @default.
• W2556223824 hasConcept C54355233 @default.
• W2556223824 hasConcept C62277055 @default.
• W2556223824 hasConcept C70721500 @default.
• W2556223824 hasConcept C78458016 @default.
• W2556223824 hasConcept C79186407 @default.
• W2556223824 hasConcept C86803240 @default.
• W2556223824 hasConcept C8891405 @default.
• W2556223824 hasConcept C94625758 @default.
• W2556223824 hasConcept C95444343 @default.

• next