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- W2556293890 abstract "Background The mechanisms of fatigue in rheumatoid arthritis (RA) are still unclear and the effect of antirheumatic drugs on fatigue not fully established. Objectives To analyse in a large cohort of RA the factors associated with fatigue focusing on social aspects, comorbidities and treatment intake. Methods Cross sectional analyses were performed on RA patients from the French cohort study of comorbidities COMEDRA (1). Fatigue was assessed as a quantitative variable (RAID3 0–10 numeric scale) or by class (acceptable Results 962 patients were analysed (age 57.7 ± 11.1 years, disease duration 11.1 years [6.2–19.1], mean DAS28 3.1 ± 1.3), 763 (79%) were female. The mean fatigue score was 3.8± 2.7. Severe fatigue was more frequent in women, in patients not working, with less physical activity and more obesity. Fatigue was correlated with disease duration (p=0.05), all disease activity index (p Conclusions Beyond the expected association of fatigue with disease activity, female gender, pain, sleep and emotional well-being, comorbidities and less physical activity could contribute to the frequent fatigue noted in RA. Fatigue was associated with steroids, NSAIDs, biotherapies but not with methotrexate and did not depend of the type of biotherapy. References Dougados M et al. Ann Rheum Dis. 2015;74(9):1725–33 Disclosure of Interest None declared" @default.
- W2556293890 created "2016-11-30" @default.
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- W2556293890 date "2016-06-01" @default.
- W2556293890 modified "2023-09-24" @default.
- W2556293890 title "FRI0106 The Association of Fatigue, Comorbidities and Anti Rheumatic Drugs in Rheumatoid Arthritis: Results from The Comedra Study" @default.
- W2556293890 doi "https://doi.org/10.1136/annrheumdis-2016-eular.2824" @default.
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