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- W2556330394 abstract "Ovarian cancer that estimated to be the top fifth leading cause of cancer death in women all over the world. Compelling evidence indicates that the immune response against ovarian cancer may play crucial role in controlling this problem. This review will discuss the recent clinical developments of selected immunotherapies for ovarian cancer.68 articles had been reviewed carefully, our findings concluded that as the results of clinical trials of the discussed antibody based immunotherapies are inconsistent, it is still too early to conclude if these drugs will be incorporated into treatment regimens against ovarian cancer. Furthermore, their true potential may lie within being strategically employed in chemo-immunotherapy regimens. Immunotherapy, the recent approach to cancer therapy, is a type of cancer's treatment that increases the defense mechanism of the human body and helps to fight cancer. Antigen- specific immunotherapy is developed from the molecular identification of the human cancer- specific antigens. The standard approaches for the cancer treatment are radiation therapy, surgery, endocrine therapy and chemotherapy. Surgery and radiation are performed at the tumor site and the effects are precise. Oral and parenteral administration for endocrine and chemotherapy produces some systemic effects. The above four systems have adverse side effects, and the chances for the recurrence of the disease is very high. 2 On the other hand, Liu et al. believe that immunotherapy does not have these adverse effects and is the most trusted one. The agents of immunotherapy are called as immunomodulators, with immunologic effectors such as mABs, cytokines and lymphocytes being used. The immune system is stimulated to destroy or reject the tumor from the body. The types of immunotherapy practiced for cancer are Dendritic cell-based immunotherapy, Adoptive T-cell therapy with tumor infiltrating lymphocytes , Vaccines and Engineering T" @default.
- W2556330394 created "2016-11-30" @default.
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- W2556330394 date "2016-01-01" @default.
- W2556330394 modified "2023-09-27" @default.
- W2556330394 title "The impact of Immunotherapy on Ovarian Cancer" @default.
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