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- W2556379974 abstract "Summary . A 40-year old man was prescribed doxycycline 200 mg once daily for the symptoms of cough and mucopurulent sputum. The patient had retrosternal chest pain one hour after the fourth dose of doxycycline. The pain increased gradually and was radiating to the back. He also had difficult and painful swallowing. Barium swallow revealed longitudinal oriented barium pool with edematous margins on the walls of the mid-esophagus. The findings are suggestive of esophageal ulceration. He is a nonsmoker, non alcoholic and no history of aspirin or non-steroidal anti inflammatory drugs (NSAIDs) intake in the past one month. There is no history of any other concomitant medication. The therapy consisted of doxycycline withdrawal along with treatment with sucralfate, famotidine and liquid antacids. His symptoms gradually disappeared within 10 days. ). In light of the strong temporal relationship between taking the drugs and the onset of the esophageal ulceration and clinical recovery of the patient on stopping the drug we believe that the event could be due to doxycycline .The strength of association was examined using the “Naranjo’s Adverse drug Reaction Probability Scale”, in which a score of +7 was obtained suggesting a ‘probable’ link." @default.
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- W2556379974 date "2008-01-01" @default.
- W2556379974 modified "2023-09-24" @default.
- W2556379974 title "ESOPHAGEAL ULCERATION ASSOCIATED WITH DOXYCYCLINE - A CASE REPORT" @default.
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