Matches in SemOpenAlex for { <https://semopenalex.org/work/W2556465970> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2556465970 endingPage "26" @default.
- W2556465970 startingPage "7" @default.
- W2556465970 abstract "Atmospheric pressure nonthermal plasma has shown great potential for medicine applications related to disease treatment. However, the microscopic interaction of the plasma particles and its associated fields with mammalian cells is still not well understood. Here, we present the first in situ observation of the fundamental processes related to the chemical changes inside live cells upon plasma irradiation, in real time. We analyze the effect of plasma dose on cell viability and on the internal chemical environment, using novel nano and molecular chemical sensors, in gliosarcoma cells. A pulsed nanosecond helium plasma jet was used as the plasma source. Our results show the accumulation of oxidative and nitrosative stress following two minutes of plasma irradiation, with the initiation of cell death only after three minutes of plasma irradiation. Moreover, the cell membrane integrity became compromised following six minutes of irradiation, which led to sudden changes in the intracellular chemical composition. We also present the first study involving the effects of plasma irradiation on lysosomes and the mitochondrial reduction potential. We observe that the intracellular accumulation of the ROS and RNS has negligible effects on the endosomal and lysosomal membrane integrity, suggesting that the cell membrane damage is likely caused by the external ROS and not by buildup of internal oxidative stress due to the irradiation. These observations illustrate the utility of nanoprobes and molecular probes in providing insight into the fundamental interaction of cold plasma with cells, thereby assisting in the interpretation of observed macroscopic effects of tissue exposed to plasma." @default.
- W2556465970 created "2016-11-30" @default.
- W2556465970 creator A5022155791 @default.
- W2556465970 creator A5024174892 @default.
- W2556465970 creator A5034604999 @default.
- W2556465970 creator A5044343262 @default.
- W2556465970 creator A5050323685 @default.
- W2556465970 creator A5051837315 @default.
- W2556465970 date "2017-01-01" @default.
- W2556465970 modified "2023-09-26" @default.
- W2556465970 title "Real-Time Monitoring of Intracellular Chemical Changes in Response to Plasma Irradiation" @default.
- W2556465970 doi "https://doi.org/10.1615/plasmamed.2016015736" @default.
- W2556465970 hasPublicationYear "2017" @default.
- W2556465970 type Work @default.
- W2556465970 sameAs 2556465970 @default.
- W2556465970 citedByCount "4" @default.
- W2556465970 countsByYear W25564659702018 @default.
- W2556465970 countsByYear W25564659702021 @default.
- W2556465970 countsByYear W25564659702023 @default.
- W2556465970 crossrefType "journal-article" @default.
- W2556465970 hasAuthorship W2556465970A5022155791 @default.
- W2556465970 hasAuthorship W2556465970A5024174892 @default.
- W2556465970 hasAuthorship W2556465970A5034604999 @default.
- W2556465970 hasAuthorship W2556465970A5044343262 @default.
- W2556465970 hasAuthorship W2556465970A5050323685 @default.
- W2556465970 hasAuthorship W2556465970A5051837315 @default.
- W2556465970 hasConcept C102747710 @default.
- W2556465970 hasConcept C111337013 @default.
- W2556465970 hasConcept C121332964 @default.
- W2556465970 hasConcept C12554922 @default.
- W2556465970 hasConcept C129713178 @default.
- W2556465970 hasConcept C1491633281 @default.
- W2556465970 hasConcept C185544564 @default.
- W2556465970 hasConcept C185592680 @default.
- W2556465970 hasConcept C2776151105 @default.
- W2556465970 hasConcept C2778106830 @default.
- W2556465970 hasConcept C28005876 @default.
- W2556465970 hasConcept C55493867 @default.
- W2556465970 hasConcept C62520636 @default.
- W2556465970 hasConcept C79879829 @default.
- W2556465970 hasConcept C82706917 @default.
- W2556465970 hasConcept C85344455 @default.
- W2556465970 hasConcept C86803240 @default.
- W2556465970 hasConceptScore W2556465970C102747710 @default.
- W2556465970 hasConceptScore W2556465970C111337013 @default.
- W2556465970 hasConceptScore W2556465970C121332964 @default.
- W2556465970 hasConceptScore W2556465970C12554922 @default.
- W2556465970 hasConceptScore W2556465970C129713178 @default.
- W2556465970 hasConceptScore W2556465970C1491633281 @default.
- W2556465970 hasConceptScore W2556465970C185544564 @default.
- W2556465970 hasConceptScore W2556465970C185592680 @default.
- W2556465970 hasConceptScore W2556465970C2776151105 @default.
- W2556465970 hasConceptScore W2556465970C2778106830 @default.
- W2556465970 hasConceptScore W2556465970C28005876 @default.
- W2556465970 hasConceptScore W2556465970C55493867 @default.
- W2556465970 hasConceptScore W2556465970C62520636 @default.
- W2556465970 hasConceptScore W2556465970C79879829 @default.
- W2556465970 hasConceptScore W2556465970C82706917 @default.
- W2556465970 hasConceptScore W2556465970C85344455 @default.
- W2556465970 hasConceptScore W2556465970C86803240 @default.
- W2556465970 hasIssue "1" @default.
- W2556465970 hasLocation W25564659701 @default.
- W2556465970 hasOpenAccess W2556465970 @default.
- W2556465970 hasPrimaryLocation W25564659701 @default.
- W2556465970 hasRelatedWork W1978103360 @default.
- W2556465970 hasRelatedWork W2025558549 @default.
- W2556465970 hasRelatedWork W2034389832 @default.
- W2556465970 hasRelatedWork W2041164141 @default.
- W2556465970 hasRelatedWork W2045308798 @default.
- W2556465970 hasRelatedWork W2088793182 @default.
- W2556465970 hasRelatedWork W2161832828 @default.
- W2556465970 hasRelatedWork W2616494871 @default.
- W2556465970 hasRelatedWork W2811334304 @default.
- W2556465970 hasRelatedWork W3174490823 @default.
- W2556465970 hasVolume "7" @default.
- W2556465970 isParatext "false" @default.
- W2556465970 isRetracted "false" @default.
- W2556465970 magId "2556465970" @default.
- W2556465970 workType "article" @default.