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- W2556482014 abstract "The Hodgkin-Huxley equations <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>1</sup> have been used extensively to derive currents through membranes of squid giant axon. The Hodgkin-Huxley model postulates two independent ensembles of molecular channels which become accessible to K <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>+</sup> and Na <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>+</sup> ion currents respectively when they change from a closed to an open configuration. The membrane conductance is directly proportional to the number of “open” channels in each ensemble. With this arrangement, the current-voltage relationship is ohmic although the membrane conductance increases as the number of open channels increases. The rate constants for the closed-open kinetics are functions of the transmembrane potential." @default.
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- W2556482014 date "1978-10-01" @default.
- W2556482014 modified "2023-09-27" @default.
- W2556482014 title "Currents from squid giant axons clamped with their action potentials" @default.
- W2556482014 doi "https://doi.org/10.1109/ceidp.1978.7728225" @default.
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