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- W2556509044 abstract "A luminescence-based biosensor allowing for multiplex measurement of metabolites in undiluted human plasma is revealed in this study. Concurrent measurement of renal function-related metabolites including creatinine, urea, uric acid and glucose in a complex sample can be achieved in a single step using specially designed compositions which were pre-distributed into the analytical cartridge and freeze-dried into reagent-free powder. The dry-reagents allow for a rapid screening for a small amount of sample down to 10 µL. The total analysis time and required sample volume for an on-cartridge measurement of four analytes are 10 min and 150µL, respectively. We demonstrated that the system provides a good sensitivity and a wide dynamic range for metabolites measurements such that it properly meets the clinical requirements. Evaluation of long-term stability was conducted to verify the shelf life and potential applicability of the developed compositions." @default.
- W2556509044 created "2016-11-30" @default.
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- W2556509044 date "2009-10-01" @default.
- W2556509044 modified "2023-09-22" @default.
- W2556509044 title "A luminometer for determination of multiple metabolites in undiluted human plasma" @default.
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- W2556509044 doi "https://doi.org/10.1109/nanomed.2009.5559110" @default.
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