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- W2556551022 abstract "Introduction: In management of hypertension, the degree of blood pressure (BP) reduction to reach recommended BP targets, is the cornerstone of successful to antihypertensive therapy (AHT) response. However, it is unclear why the two people whose same control of BP consume different amount of antihypertensive drugs (AHD). Hypomagnesemia has been linked with hypertension. Epidemiological studies have demonstrated an inverse association between BP and serum magnesium. The aim of this study was to evaluate the BP- response to AHT which is assessed by total of AHD can be predicted by the serum magnesium in chronic hemodialysis patient. Methods: This cross-sectional study was conducted on 121 outpatient in Rasyida Hemodialysis Center. Laboratory assessment was performed before hemodialysis session. The independent t test was used to compare of quantitative data. The categorical outcome variables were compared using the chi-square test. The Pearson correlation test was used for quantitative variables. Differences were significant when P value <0.05. Results: The mean age was 54.2 ± 9.2 years, and 81 (66.9%) were men. The mean serum magnesium was 2.56 ± 0.67 mg/dL (range, 1.2 to 5.3 mg/dL). Of the 121 patients, 13 (10.7%) had hypomagnesemia, 68 (56.2%) had normomagnesemia and 40 (33.1%) had hypermagnesemia. There were no differences in serum magnesium between patients with a few and many drugs of AHD, sex, history of hypertension and diabetes. Serum magnesium significantly different in dialysis frequency, mean 2.71 ± 0.64 (two times a week, 5 hours) compare 2.31 ± 0.66 (three times a week, 4 hours). There were no correlations between serum magnesium and body mass index, calcium, phosphorus, albumin, phase angle and urea reduction ratio. Serum magnesium significantly correlated with age (r = −0.29, P < .05) and dialysis duration (r = −0.20, P < .02). Conclusion: There were no association between serum magnesium levels and total of AHD as evaluation of the BP- response to AHT." @default.
- W2556551022 created "2016-11-30" @default.
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- W2556551022 date "2015-06-01" @default.
- W2556551022 modified "2023-09-26" @default.
- W2556551022 title "Is blood magnesium level associated with total of antihypertensive drugs in chronic hemodialysis patient?" @default.
- W2556551022 doi "https://doi.org/10.1097/01.hjh.0000469821.40974.0e" @default.
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