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- W2556557868 abstract "Following tracheotomy the airways lack a mechanism of warming and humidifying the inspired air. Nebulization of saline is a common clinical practice to prevent desiccation of airways. The aim of the study was to compare cold-air-nebulization (CAN) and heated humidification (HH) on cilia activity and the necessary healthcare support. Method: Tracheotomised patients (n=19) were randomized to conventional CAN with a jet nebulizer as a control or HH (T 37 C, RH 100%) with high flow of air (30 L/min) delivered with the AIRVO2 blower-humidifier (F&P Healthcare, NZ). The ciliary beat frequency (CBF) in tracheal epithelial cells was measured in vitro using videomicroscopy on day 2, 4, 6, 8 and 10 following the tracheotomy. Number of suctioning procedures per day to clean the trachea from the excessive mucus was assessed. Results: Data are medians (range). CBF was significantly (p<0.001) higher in the HH group 5,9 (14,2) Hz compared to the CAN group 3,9 (10,5) Hz. Differences in CBF were statistically significant (p Conclusion: Results indicate a potential advantage of hydration with heated humidified air over the conventional nebulization of cold saline in the first 10 days following tracheotomy." @default.
- W2556557868 created "2016-11-30" @default.
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- W2556557868 date "2016-09-01" @default.
- W2556557868 modified "2023-09-26" @default.
- W2556557868 title "Heated air humidification vs. cold air nebulisation in tracheotomised patients increases cilia beat frequency in tracheal epithelium and reduces frequency of suctioning procedures" @default.
- W2556557868 doi "https://doi.org/10.1183/13993003.congress-2016.pa3751" @default.
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