FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2556968286> ?p ?o ?g. }

• W2556968286 endingPage "498" @default.
• W2556968286 startingPage "492" @default.
• W2556968286 abstract "Aims To investigate the status of somatostatin receptors ( SSTR s) in resected hepatocellular carcinoma ( HCC ). Methods and results Transcript and protein levels of SSTR 2, SSTR 3 and SSTR 5 were investigated, with real‐time polymerase chain reaction ( PCR ) and manual and automated immunohistochemistry ( IHC ), in 53 resected HCC s and paired non‐tumour tissues. SSTR 1, SSTR 4, SSTR 5 TMD 4 and SSTR 5 TMD 5 were analysed with real‐time PCR . SSTR 3 and SSTR 5 transcripts were expressed in ~25% of HCC s, but not in adjacent non‐tumour tissues. SSTR 1 and SSTR 2 transcripts were overexpressed in 42% and 32% of HCC s, respectively. SSTR 4, SSTR 5 TMD 4 and SSTR 5 TMD 5 were not detected. Membrane staining for SSTR 2 was detected in 38% of HCC s, whereas SSTR 5 protein was detectable in only 11% of HCC s. SSTR 3 protein was detected in the majority of HCC s and adjacent non‐tumour liver tissues, but membrane staining was <20% of that in HCC s. The results obtained with the two IHC methods were highly correlated ( P < 0.0001). Statistical analyses also showed a positive correlation between SSTR 2 membrane staining and cytokeratin 19 expression ( P = 0.04), serum α‐fetoprotein level ( P = 0.002), and poor differentiation ( P = 0.05). Conclusions Membrane SSTR 2 is detected reliably in HCC s by IHC , and is a potential therapeutic target, as it is coexpressed with markers of poor prognosis." @default.
• W2556968286 created "2016-11-30" @default.
• W2556968286 creator A5010913991 @default.
• W2556968286 creator A5020985866 @default.
• W2556968286 creator A5025492450 @default.
• W2556968286 creator A5029727859 @default.
• W2556968286 creator A5038091663 @default.
• W2556968286 creator A5041662580 @default.
• W2556968286 creator A5043245662 @default.
• W2556968286 creator A5051847570 @default.
• W2556968286 creator A5052559713 @default.
• W2556968286 creator A5057385196 @default.
• W2556968286 creator A5074178383 @default.
• W2556968286 date "2016-11-10" @default.
• W2556968286 modified "2023-10-18" @default.
• W2556968286 title "Somatostatin receptors in resected hepatocellular carcinoma: status and correlation with markers of poor prognosis" @default.
• W2556968286 cites W1967441142 @default.
• W2556968286 cites W1970726875 @default.
• W2556968286 cites W1975792622 @default.
• W2556968286 cites W1984087164 @default.
• W2556968286 cites W1985377196 @default.
• W2556968286 cites W1990073288 @default.
• W2556968286 cites W1996277662 @default.
• W2556968286 cites W2002906231 @default.
• W2556968286 cites W2004250245 @default.
• W2556968286 cites W2005394309 @default.
• W2556968286 cites W2006260944 @default.
• W2556968286 cites W2012408740 @default.
• W2556968286 cites W2020818891 @default.
• W2556968286 cites W2026390023 @default.
• W2556968286 cites W2028959660 @default.
• W2556968286 cites W2029378031 @default.
• W2556968286 cites W2033622182 @default.
• W2556968286 cites W2037245133 @default.
• W2556968286 cites W2046171915 @default.
• W2556968286 cites W2052344891 @default.
• W2556968286 cites W2054500254 @default.
• W2556968286 cites W2063493635 @default.
• W2556968286 cites W2073329174 @default.
• W2556968286 cites W2074004139 @default.
• W2556968286 cites W2074607936 @default.
• W2556968286 cites W2081909579 @default.
• W2556968286 cites W2085931229 @default.
• W2556968286 cites W2086184537 @default.
• W2556968286 cites W2088486874 @default.
• W2556968286 cites W2094466065 @default.
• W2556968286 cites W2129462305 @default.
• W2556968286 cites W2135049144 @default.
• W2556968286 cites W2139814003 @default.
• W2556968286 cites W2154775438 @default.
• W2556968286 cites W2162533224 @default.
• W2556968286 cites W2163403599 @default.
• W2556968286 cites W2165324593 @default.
• W2556968286 cites W2321984805 @default.
• W2556968286 doi "https://doi.org/10.1111/his.13034" @default.
• W2556968286 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27391928" @default.
• W2556968286 hasPublicationYear "2016" @default.
• W2556968286 type Work @default.
• W2556968286 sameAs 2556968286 @default.
• W2556968286 citedByCount "10" @default.
• W2556968286 countsByYear W25569682862019 @default.
• W2556968286 countsByYear W25569682862020 @default.
• W2556968286 countsByYear W25569682862021 @default.
• W2556968286 countsByYear W25569682862023 @default.
• W2556968286 crossrefType "journal-article" @default.
• W2556968286 hasAuthorship W2556968286A5010913991 @default.
• W2556968286 hasAuthorship W2556968286A5020985866 @default.
• W2556968286 hasAuthorship W2556968286A5025492450 @default.
• W2556968286 hasAuthorship W2556968286A5029727859 @default.
• W2556968286 hasAuthorship W2556968286A5038091663 @default.
• W2556968286 hasAuthorship W2556968286A5041662580 @default.
• W2556968286 hasAuthorship W2556968286A5043245662 @default.
• W2556968286 hasAuthorship W2556968286A5051847570 @default.
• W2556968286 hasAuthorship W2556968286A5052559713 @default.
• W2556968286 hasAuthorship W2556968286A5057385196 @default.
• W2556968286 hasAuthorship W2556968286A5074178383 @default.
• W2556968286 hasConcept C126322002 @default.
• W2556968286 hasConcept C142724271 @default.
• W2556968286 hasConcept C170493617 @default.
• W2556968286 hasConcept C204232928 @default.
• W2556968286 hasConcept C2778019345 @default.
• W2556968286 hasConcept C2779012181 @default.
• W2556968286 hasConcept C71924100 @default.
• W2556968286 hasConcept C74864618 @default.
• W2556968286 hasConcept C80115893 @default.
• W2556968286 hasConceptScore W2556968286C126322002 @default.
• W2556968286 hasConceptScore W2556968286C142724271 @default.
• W2556968286 hasConceptScore W2556968286C170493617 @default.
• W2556968286 hasConceptScore W2556968286C204232928 @default.
• W2556968286 hasConceptScore W2556968286C2778019345 @default.
• W2556968286 hasConceptScore W2556968286C2779012181 @default.
• W2556968286 hasConceptScore W2556968286C71924100 @default.
• W2556968286 hasConceptScore W2556968286C74864618 @default.
• W2556968286 hasConceptScore W2556968286C80115893 @default.
• W2556968286 hasFunder F4320320614 @default.
• W2556968286 hasFunder F4320320893 @default.
• W2556968286 hasIssue "3" @default.
• W2556968286 hasLocation W25569682861 @default.

• next