Matches in SemOpenAlex for { <https://semopenalex.org/work/W2556973443> ?p ?o ?g. }
- W2556973443 endingPage "223" @default.
- W2556973443 startingPage "214" @default.
- W2556973443 abstract "In this article, we address a fundamental question regarding computational fluid dynamics (CFD) modeling within lung airways: does the inhaled volume during imaging have a significant effect on CFD computations of aerosol deposition? High resolution computed tomography (HRCT) images taken at mean lung volume (MLV) and at total lung capacity (TLC) obtained as part of a previous study of ventilation and aerosol deposition using positron emission tomography (PET) in challenged asthmatics were utilized to construct two airway models for each subject, and the differences in CFD calculated deposition metrics were subsequently quantified. These models included all the airway generations that could be rendered from the HRCT images. CFD calculations for three inhalation flow rates and four monodisperse aerosol sizes used images at MLV and at TLC from 24 volunteer subjects. Both large scale and detailed measures of particle deposition distribution were used in the analysis. The influence of lung volume during imaging is to increase airway dimensions in realistic models and thus reduce flow velocity and deposition due to impaction in the upper airways as calculated by CFD. However, large-scale deposition measures are confounded when the TLC models include deeper generations in the lung that increase the total airway deposition. These trends are modulated by the flow and particle characteristics of the aerosol, making consistent quantifiable differences between MLV and TLC difficult to predict unless both models consider the same anatomical airways.© 2017 American Association for Aerosol Research" @default.
- W2556973443 created "2016-11-30" @default.
- W2556973443 creator A5008201050 @default.
- W2556973443 creator A5012604935 @default.
- W2556973443 creator A5015133506 @default.
- W2556973443 creator A5019516030 @default.
- W2556973443 creator A5024920660 @default.
- W2556973443 creator A5045655641 @default.
- W2556973443 creator A5072358691 @default.
- W2556973443 date "2016-11-18" @default.
- W2556973443 modified "2023-10-15" @default.
- W2556973443 title "The influence of lung volume during imaging on CFD within realistic airway models" @default.
- W2556973443 cites W1427873363 @default.
- W2556973443 cites W1493274789 @default.
- W2556973443 cites W1649122172 @default.
- W2556973443 cites W1750710754 @default.
- W2556973443 cites W1812208392 @default.
- W2556973443 cites W1967957900 @default.
- W2556973443 cites W1975708769 @default.
- W2556973443 cites W2008624656 @default.
- W2556973443 cites W2009198143 @default.
- W2556973443 cites W2019658471 @default.
- W2556973443 cites W2032488946 @default.
- W2556973443 cites W2037018943 @default.
- W2556973443 cites W2041472021 @default.
- W2556973443 cites W2042636660 @default.
- W2556973443 cites W2048772048 @default.
- W2556973443 cites W2050199502 @default.
- W2556973443 cites W2050522776 @default.
- W2556973443 cites W2052109061 @default.
- W2556973443 cites W2053407905 @default.
- W2556973443 cites W2056405843 @default.
- W2556973443 cites W2061374304 @default.
- W2556973443 cites W2074976027 @default.
- W2556973443 cites W2075191063 @default.
- W2556973443 cites W2079810636 @default.
- W2556973443 cites W2082916331 @default.
- W2556973443 cites W2104041174 @default.
- W2556973443 cites W2108290557 @default.
- W2556973443 cites W2115229157 @default.
- W2556973443 cites W2136199835 @default.
- W2556973443 cites W2138042009 @default.
- W2556973443 cites W2145526619 @default.
- W2556973443 cites W2150805640 @default.
- W2556973443 cites W2156647462 @default.
- W2556973443 cites W2158290291 @default.
- W2556973443 cites W2169229115 @default.
- W2556973443 cites W2172156413 @default.
- W2556973443 cites W2259952988 @default.
- W2556973443 cites W2262816522 @default.
- W2556973443 cites W2326852041 @default.
- W2556973443 cites W2485036015 @default.
- W2556973443 cites W3168772697 @default.
- W2556973443 doi "https://doi.org/10.1080/02786826.2016.1254721" @default.
- W2556973443 hasPublicationYear "2016" @default.
- W2556973443 type Work @default.
- W2556973443 sameAs 2556973443 @default.
- W2556973443 citedByCount "7" @default.
- W2556973443 countsByYear W25569734432018 @default.
- W2556973443 countsByYear W25569734432019 @default.
- W2556973443 countsByYear W25569734432020 @default.
- W2556973443 countsByYear W25569734432021 @default.
- W2556973443 countsByYear W25569734432022 @default.
- W2556973443 crossrefType "journal-article" @default.
- W2556973443 hasAuthorship W2556973443A5008201050 @default.
- W2556973443 hasAuthorship W2556973443A5012604935 @default.
- W2556973443 hasAuthorship W2556973443A5015133506 @default.
- W2556973443 hasAuthorship W2556973443A5019516030 @default.
- W2556973443 hasAuthorship W2556973443A5024920660 @default.
- W2556973443 hasAuthorship W2556973443A5045655641 @default.
- W2556973443 hasAuthorship W2556973443A5072358691 @default.
- W2556973443 hasBestOaLocation W25569734431 @default.
- W2556973443 hasConcept C105922876 @default.
- W2556973443 hasConcept C121332964 @default.
- W2556973443 hasConcept C126322002 @default.
- W2556973443 hasConcept C127313418 @default.
- W2556973443 hasConcept C136229726 @default.
- W2556973443 hasConcept C141071460 @default.
- W2556973443 hasConcept C151730666 @default.
- W2556973443 hasConcept C153294291 @default.
- W2556973443 hasConcept C1633027 @default.
- W2556973443 hasConcept C20556612 @default.
- W2556973443 hasConcept C27101514 @default.
- W2556973443 hasConcept C2777714996 @default.
- W2556973443 hasConcept C2779345167 @default.
- W2556973443 hasConcept C2816523 @default.
- W2556973443 hasConcept C2961886 @default.
- W2556973443 hasConcept C39432304 @default.
- W2556973443 hasConcept C57879066 @default.
- W2556973443 hasConcept C62520636 @default.
- W2556973443 hasConcept C64297162 @default.
- W2556973443 hasConcept C71924100 @default.
- W2556973443 hasConceptScore W2556973443C105922876 @default.
- W2556973443 hasConceptScore W2556973443C121332964 @default.
- W2556973443 hasConceptScore W2556973443C126322002 @default.
- W2556973443 hasConceptScore W2556973443C127313418 @default.
- W2556973443 hasConceptScore W2556973443C136229726 @default.
- W2556973443 hasConceptScore W2556973443C141071460 @default.