Matches in SemOpenAlex for { <https://semopenalex.org/work/W2557204622> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2557204622 abstract "BACKGROUND In 2011, following a period with delivery problems, the only registered digitoxin drug in Norway was replaced with digoxin. As a result, approximately 21 000 patients had to replace digitoxin with digoxin. There are important pharmacokinetic differences between digitoxin and digoxin (the general term for both drugs is digitalis), which must be taken into account when changing therapy. The aim of this study was to investigate compliance of drug security, during the transition from digitoxin to digoxin in Norway.MATERIAL AND METHOD Enquiries addressed to the Norwegian Poison Information Centre and reports of fatal adverse effects to the Regional Drug Information Centres (RELIS) regarding intake of digitalis were analysed. Serum concentrations of digitoxin and digoxin analyzed at Oslo University Hospital were reviewed. All data sources were reviewed for the years 2010-2014 and patients > 20 years were included.RESULTS The total number of enquiries addressed to the Norwegian Poison Information Centre, fatal adverse drug reactions reported to RELIS, and patient samples in the toxic range analyzed at Oslo University Hospital increased from 2012, timewise related to the transition to digoxin.INTERPRETATION Despite extensive information from the Norwegian Medicines Agency, a small, transient increase was observed in the number of overdoses and reported deaths from digitalis related to change in therapy. The cause of the overdose was in many cases unknown. This study revealed several cases of incorrect dosage, simultaneous use of digitoxin and digoxin, and washout time that was insufficient or lacking before initiation of digoxin." @default.
- W2557204622 created "2016-11-30" @default.
- W2557204622 creator A5011940928 @default.
- W2557204622 creator A5014341222 @default.
- W2557204622 creator A5042420829 @default.
- W2557204622 creator A5052713057 @default.
- W2557204622 creator A5063236207 @default.
- W2557204622 date "2016-01-01" @default.
- W2557204622 modified "2023-09-27" @default.
- W2557204622 title "Legemiddelsikkerhet ved bytte av digitalispreparat i Norge" @default.
- W2557204622 cites W100651095 @default.
- W2557204622 cites W1968030991 @default.
- W2557204622 cites W2090356792 @default.
- W2557204622 cites W2148671901 @default.
- W2557204622 cites W2150184024 @default.
- W2557204622 cites W2157956154 @default.
- W2557204622 cites W2404452441 @default.
- W2557204622 doi "https://doi.org/10.4045/tidsskr.15.0161" @default.
- W2557204622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27830905" @default.
- W2557204622 hasPublicationYear "2016" @default.
- W2557204622 type Work @default.
- W2557204622 sameAs 2557204622 @default.
- W2557204622 citedByCount "3" @default.
- W2557204622 countsByYear W25572046222016 @default.
- W2557204622 countsByYear W25572046222017 @default.
- W2557204622 countsByYear W25572046222022 @default.
- W2557204622 crossrefType "journal-article" @default.
- W2557204622 hasAuthorship W2557204622A5011940928 @default.
- W2557204622 hasAuthorship W2557204622A5014341222 @default.
- W2557204622 hasAuthorship W2557204622A5042420829 @default.
- W2557204622 hasAuthorship W2557204622A5052713057 @default.
- W2557204622 hasAuthorship W2557204622A5063236207 @default.
- W2557204622 hasBestOaLocation W25572046221 @default.
- W2557204622 hasConcept C126322002 @default.
- W2557204622 hasConcept C194828623 @default.
- W2557204622 hasConcept C2776445394 @default.
- W2557204622 hasConcept C2777707475 @default.
- W2557204622 hasConcept C2778198053 @default.
- W2557204622 hasConcept C2780035454 @default.
- W2557204622 hasConcept C2780628665 @default.
- W2557204622 hasConcept C71924100 @default.
- W2557204622 hasConcept C98274493 @default.
- W2557204622 hasConceptScore W2557204622C126322002 @default.
- W2557204622 hasConceptScore W2557204622C194828623 @default.
- W2557204622 hasConceptScore W2557204622C2776445394 @default.
- W2557204622 hasConceptScore W2557204622C2777707475 @default.
- W2557204622 hasConceptScore W2557204622C2778198053 @default.
- W2557204622 hasConceptScore W2557204622C2780035454 @default.
- W2557204622 hasConceptScore W2557204622C2780628665 @default.
- W2557204622 hasConceptScore W2557204622C71924100 @default.
- W2557204622 hasConceptScore W2557204622C98274493 @default.
- W2557204622 hasLocation W25572046221 @default.
- W2557204622 hasLocation W25572046222 @default.
- W2557204622 hasOpenAccess W2557204622 @default.
- W2557204622 hasPrimaryLocation W25572046221 @default.
- W2557204622 hasRelatedWork W109739913 @default.
- W2557204622 hasRelatedWork W1480780884 @default.
- W2557204622 hasRelatedWork W1642869554 @default.
- W2557204622 hasRelatedWork W2013682012 @default.
- W2557204622 hasRelatedWork W2017968437 @default.
- W2557204622 hasRelatedWork W2025181812 @default.
- W2557204622 hasRelatedWork W2043006463 @default.
- W2557204622 hasRelatedWork W2056620103 @default.
- W2557204622 hasRelatedWork W2056725644 @default.
- W2557204622 hasRelatedWork W2061007693 @default.
- W2557204622 hasRelatedWork W2073321635 @default.
- W2557204622 hasRelatedWork W2161652624 @default.
- W2557204622 hasRelatedWork W2205739244 @default.
- W2557204622 hasRelatedWork W2253894222 @default.
- W2557204622 hasRelatedWork W2301999761 @default.
- W2557204622 hasRelatedWork W2771570657 @default.
- W2557204622 hasRelatedWork W3010692646 @default.
- W2557204622 hasRelatedWork W3121756901 @default.
- W2557204622 hasRelatedWork W345281505 @default.
- W2557204622 hasRelatedWork W2187552950 @default.
- W2557204622 isParatext "false" @default.
- W2557204622 isRetracted "false" @default.
- W2557204622 magId "2557204622" @default.
- W2557204622 workType "article" @default.