Matches in SemOpenAlex for { <https://semopenalex.org/work/W2557407741> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2557407741 abstract "Objectives: The aim of this work is to study the effects, adverse effects and recovery time of IV mixed propofol and ketamine (ketofol) in 3:1 ratio as a sedative analgesic in children with acute lymphoblastic leukemia undergoing bone marrow aspiration.Methods: This was a prospective, observational pilot study of twenty patients; 3-12 years with ALL requiring sedation for BMA were included. Mixture of ketofol (3:1) was administered intravenously in a dose of 0.5 mg⁄kg at 30-second to 1-minute intervals aiming to achieve a sedation level of 3 or 4 on Ramsay scale to start the procedure. Patient satisfaction was the primary outcome in our study. Faces pain scale-revised (FPS-R) was used to assess the degree of analgesia. Secondary outcomes included sedation time, recovery time, adverse events and safety.Results: 20 patients were enrolled for the study. The median dose of ketofol is 3 mg/kg of propofol and 1 mg/kg of ketamine with no patients required extra doses. The median score on the pain faces scale was (comfortable) (1-3; 95% CI 1.08-2.92). Median recovery time was 22 minutes (16-30; 95% CI 14.08-29.32). The cardiorespiratory adverse events were transient, tolerable and easily corrected.Conclusion: Combination of ketamine and propofol in the same syringe in this pilot study produced effective sedation, which is illustrated by the degree of satisfaction shown by patients. Moreover, rapid recovery and absence of clinically significant adverse events were noticed among children requiring procedural sedation and analgesia for bone marrow aspiration. A high recommendation of using large sample size should be considered for further assessment and verification of our results." @default.
- W2557407741 created "2016-12-08" @default.
- W2557407741 creator A5005338754 @default.
- W2557407741 creator A5022871652 @default.
- W2557407741 creator A5055956376 @default.
- W2557407741 creator A5086111986 @default.
- W2557407741 date "2015-01-01" @default.
- W2557407741 modified "2023-09-27" @default.
- W2557407741 title "Ketofol for Procedural Sedation and Analgesia in Children with Acute Lymphoblastic Leukemia" @default.
- W2557407741 cites W115108213 @default.
- W2557407741 cites W1656168588 @default.
- W2557407741 cites W1760105068 @default.
- W2557407741 cites W1826658735 @default.
- W2557407741 cites W1972751107 @default.
- W2557407741 cites W1973798824 @default.
- W2557407741 cites W1983156829 @default.
- W2557407741 cites W1990227001 @default.
- W2557407741 cites W1991033625 @default.
- W2557407741 cites W1994017467 @default.
- W2557407741 cites W1997099325 @default.
- W2557407741 cites W2003991829 @default.
- W2557407741 cites W2013976047 @default.
- W2557407741 cites W2015750811 @default.
- W2557407741 cites W2025661585 @default.
- W2557407741 cites W2030866261 @default.
- W2557407741 cites W2032051250 @default.
- W2557407741 cites W2032646983 @default.
- W2557407741 cites W2045496900 @default.
- W2557407741 cites W2059805696 @default.
- W2557407741 cites W2061893314 @default.
- W2557407741 cites W2062177062 @default.
- W2557407741 cites W2062394761 @default.
- W2557407741 cites W2064194588 @default.
- W2557407741 cites W2065016579 @default.
- W2557407741 cites W2076834292 @default.
- W2557407741 cites W2080753945 @default.
- W2557407741 cites W2081800185 @default.
- W2557407741 cites W2094230303 @default.
- W2557407741 cites W2098232948 @default.
- W2557407741 cites W2099007110 @default.
- W2557407741 cites W2103978352 @default.
- W2557407741 cites W2105159031 @default.
- W2557407741 cites W2107515212 @default.
- W2557407741 cites W2111130915 @default.
- W2557407741 cites W2114796727 @default.
- W2557407741 cites W2115238070 @default.
- W2557407741 cites W2116695043 @default.
- W2557407741 cites W2128126559 @default.
- W2557407741 cites W2139580351 @default.
- W2557407741 cites W2147481630 @default.
- W2557407741 cites W2150165501 @default.
- W2557407741 cites W2154357825 @default.
- W2557407741 cites W2300209561 @default.
- W2557407741 cites W2479158033 @default.
- W2557407741 doi "https://doi.org/10.4172/2155-6148.1000515" @default.
- W2557407741 hasPublicationYear "2015" @default.
- W2557407741 type Work @default.
- W2557407741 sameAs 2557407741 @default.
- W2557407741 citedByCount "5" @default.
- W2557407741 countsByYear W25574077412015 @default.
- W2557407741 crossrefType "journal-article" @default.
- W2557407741 hasAuthorship W2557407741A5005338754 @default.
- W2557407741 hasAuthorship W2557407741A5022871652 @default.
- W2557407741 hasAuthorship W2557407741A5055956376 @default.
- W2557407741 hasAuthorship W2557407741A5086111986 @default.
- W2557407741 hasBestOaLocation W25574077411 @default.
- W2557407741 hasConcept C126322002 @default.
- W2557407741 hasConcept C2776814716 @default.
- W2557407741 hasConcept C2778461978 @default.
- W2557407741 hasConcept C2909962599 @default.
- W2557407741 hasConcept C42219234 @default.
- W2557407741 hasConcept C71924100 @default.
- W2557407741 hasConceptScore W2557407741C126322002 @default.
- W2557407741 hasConceptScore W2557407741C2776814716 @default.
- W2557407741 hasConceptScore W2557407741C2778461978 @default.
- W2557407741 hasConceptScore W2557407741C2909962599 @default.
- W2557407741 hasConceptScore W2557407741C42219234 @default.
- W2557407741 hasConceptScore W2557407741C71924100 @default.
- W2557407741 hasIssue "03" @default.
- W2557407741 hasLocation W25574077411 @default.
- W2557407741 hasOpenAccess W2557407741 @default.
- W2557407741 hasPrimaryLocation W25574077411 @default.
- W2557407741 hasRelatedWork W2000717433 @default.
- W2557407741 hasRelatedWork W2028351919 @default.
- W2557407741 hasRelatedWork W2040495353 @default.
- W2557407741 hasRelatedWork W2330750108 @default.
- W2557407741 hasRelatedWork W2407161884 @default.
- W2557407741 hasRelatedWork W2410889947 @default.
- W2557407741 hasRelatedWork W2549135832 @default.
- W2557407741 hasRelatedWork W2801518877 @default.
- W2557407741 hasRelatedWork W2981645800 @default.
- W2557407741 hasRelatedWork W4249127011 @default.
- W2557407741 hasVolume "06" @default.
- W2557407741 isParatext "false" @default.
- W2557407741 isRetracted "false" @default.
- W2557407741 magId "2557407741" @default.
- W2557407741 workType "article" @default.