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- W2557432935 abstract "The design and synthesis of oligoamide α-helix peptidomimetics is reported. The oligoamide type systems are prepared in a modular fashion by coupling the monomers using palladium-catalyzed carbonylation chemistry. This enabled us to use substrates with a low nucleophilicity, leading to previously unreported pyrazine based oligoamide α-helix mimetics. The proof of principle is given by synthesizing a small set of compounds. Various end-capping groups were introduced and also a mixed multimer was successfully prepared." @default.
- W2557432935 created "2016-12-08" @default.
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- W2557432935 date "2017-01-01" @default.
- W2557432935 modified "2023-09-26" @default.
- W2557432935 title "Carbonylation as a novel method for the assembly of pyrazine based oligoamide alpha-helix mimetics" @default.
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- W2557432935 doi "https://doi.org/10.1039/c6ob02358d" @default.
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