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- W2557598942 abstract "The phenomenon of hematogenous tumor cell dissemination in patients with solid tumors has been extensively explored over the last decades. Breast cancer research investigated at first disseminated tumor cells (DTCs) in the bone marrow; however, the focus soon moved to circulating tumor cells (CTCs) in the peripheral blood as blood is easily accessible without an invasive procedure. The prognostic significance of CTC presence has been shown in large studies both in adjuvant and metastatic setting and commercially available detection assays have been evaluated for monitoring in clinical trials. Beyond detection and enumeration of CTCs, the characterization of single tumor cells may enhance our knowledge on disease progression and thus optimize treatment choices." @default.
- W2557598942 created "2016-12-08" @default.
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- W2557598942 date "2016-12-01" @default.
- W2557598942 modified "2023-10-01" @default.
- W2557598942 title "Potential Role of Circulating Tumor Cell Detection and Monitoring in Breast Cancer: A Review of Current Evidence" @default.
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- W2557598942 doi "https://doi.org/10.3389/fonc.2016.00255" @default.
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