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- W2557825113 abstract "Loin pain haematuria syndrome is a descriptive diagnosis of recurrent episodes of loin pain accompanied by haematufia, in which investigations do not reveal ade- quate pathology to account for the symptoms, The majority of patients present between 20 and 40 years, but onset may occur in older children. A significant number of patients show psychological and psychopathological features. Renal �9 histology may show minor abnormalities, including me- sangial proliferation, arteriolar and arterial hyalinosis and C3 in arterioles. Renal angiography is often normal but changes in intrarenal arterioles and cortical infarcts may be seen. Haematological abnormalities include decreased heparin-thrombin clotting time and elevated free plasma serotonin concentration. It is important that the assessment include a detailed psychiatric history, the patient's percep- tion of pain, and the psychosocial environment. The pain may be very severe, leading to the requirement for addic- tive analgesics: management often becomes very difficult and frustrating to medical practitioners. Surgical interven- tion with capsulotomy, denervation and autotransplantation should only be considered as a last resort, as there is fre- quent recurrence of pain on the same or contralateral side." @default.
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- W2557825113 date "1996-01-01" @default.
- W2557825113 modified "2023-09-24" @default.
- W2557825113 title "Practical Pediatric Nephrology Loin pain haematuria syndrome" @default.
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