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- W2558287021 abstract "The biophysical properties and behavior of natural calf thymus DNA in hydrated 1-ethyl-3-butylimidazolium bromide ionic liquid ([C2bim]Br) have been studied using spectroscopy technique. The effect of ionic liquid concentration and temperature towards the duplex B-DNA conformation were determined. The presence of ionic liquid causes higher duplex DNA stability with the DNA melting temperature of ∼56°C without any addition of buffer solutions. The electrostatic attraction between ionic liquid’s cation and DNA phosphates groups was found play a main role in stabilizing native DNA structure. Understanding of the biophysical properties of DNA in this ionic media could be used as a platform for future development of specific solvent for nucleic acid nanotechnology." @default.
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- W2558287021 date "2016-01-01" @default.
- W2558287021 modified "2023-10-14" @default.
- W2558287021 title "Biophysical properties of DNA in hydrated ionic liquids" @default.
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- W2558287021 doi "https://doi.org/10.1063/1.4968137" @default.
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