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- W2558342382 abstract "No AccessJournal of UrologyPediatric Urology1 Apr 2017Prognostic Value of Ultrasound Grading Systems in Prenatally Diagnosed Unilateral Urinary Tract Dilatation Aurélien Scalabre, Delphine Demède, Ségolène Gaillard, Jean-Pierre Pracros, Pierre Mouriquand, and Pierre-Yves Mure Aurélien ScalabreAurélien Scalabre Pediatric Surgery Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author , Delphine DemèdeDelphine Demède Pediatric Surgery Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author , Ségolène GaillardSégolène Gaillard Epicime-Clinical Investigation Center 1407 de Lyon, Inserm, Service de Pharmacologie Clinique, CHU Lyon, Bron, France Laboratory of Biometrics and Evolutionary Biology, National Center for Scientific Research, UMR 5558, Villeurbanne, France More articles by this author , Jean-Pierre PracrosJean-Pierre Pracros Pediatric Radiology Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author , Pierre MouriquandPierre Mouriquand Pediatric Surgery Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author , and Pierre-Yves MurePierre-Yves Mure Pediatric Surgery Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.11.103AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We compared the prognostic value of anteroposterior intrasinus diameter of the renal pelvis, urinary tract dilatation and the Society for Fetal Urology grading system in children with prenatally diagnosed unilateral urinary tract dilatation. Materials and Methods: All newborns with prenatally diagnosed unilateral urinary tract dilatation, normal bladder and anteroposterior intrasinus diameter 10 mm or greater on the first postnatal ultrasonography were prospectively enrolled from January 2011 to February 2015. Indications for surgery were recurrent febrile urinary tract infections and/or decrease of relative renal function more than 10% on serial isotope studies and/or increasing anteroposterior intrasinus diameter greater than 20% on serial ultrasounds. Sensitivity, specificity and ROC curves were calculated to evaluate the accuracy of anteroposterior intrasinus diameter, urinary tract dilatation and Society for Fetal Urology grading system in determining which children would need surgery within 24 months. Results: A total of 57 males and 13 females were included. Of the patients 33 required surgery at a median age of 5 months (IQR 3.8 to 6.4). Urinary tract dilatation remained stable in 14 cases and decreased in 23 with a median followup of 42 months (IQR 25 to 67). Anteroposterior intrasinus diameter, urinary tract dilatation and Society for Fetal Urology scores were all correlated with the need for surgery. Anteroposterior intrasinus diameter with a threshold of 20 mm had the best prognostic value, with a sensitivity of 81.8% and a specificity of 91.7%. Conclusions: Our study confirms that the prognostic value was comparable between anteroposterior intrasinus diameter of the renal pelvis, urinary tract dilatation and Society for Fetal Urology grading system in newborns with prenatally diagnosed unilateral urinary tract dilatation. Anteroposterior intrasinus diameter and abnormal parenchymal thickness are the most important ultrasound criteria to identify children at risk for requiring surgery. References 1 : Upper urinary tract dilatation: prenatal diagnosis, management and outcome. Semin Fetal Neonatal Med2008; 13: 152. 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Google Scholar 25 : The outcome of antenatal ultrasound diagnosed anomalies of the kidney and urinary tract in a large Danish birth cohort. Arch Dis Child2016; 101: 819. Google Scholar © 2017 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byMelo F, Mak R, Simões e Silva A, Vasconcelos M, Dias C, Rosa L, Shiomatsu G, Storch C, Oliveira M and Oliveira E (2021) Evaluation of Urinary Tract Dilation Classification System for Prediction of Long-Term Outcomes in Isolated Antenatal Hydronephrosis: A Cohort StudyJournal of Urology, VOL. 206, NO. 4, (1022-1030), Online publication date: 1-Oct-2021.Cain M (2017) This Month in Pediatric UrologyJournal of Urology, VOL. 197, NO. 4, (971-972), Online publication date: 1-Apr-2017. Volume 197Issue 4April 2017Page: 1144-1149Supplementary Materials Advertisement Copyright & Permissions© 2017 by American Urological Association Education and Research, Inc.Keywordsurinary tractinfantdilatationkidney pelvisnewbornhydronephrosisAcknowledgmentsDr. Mehdi Benchaib assisted with statistical analysis.MetricsAuthor Information Aurélien Scalabre Pediatric Surgery Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author Delphine Demède Pediatric Surgery Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author Ségolène Gaillard Epicime-Clinical Investigation Center 1407 de Lyon, Inserm, Service de Pharmacologie Clinique, CHU Lyon, Bron, France Laboratory of Biometrics and Evolutionary Biology, National Center for Scientific Research, UMR 5558, Villeurbanne, France More articles by this author Jean-Pierre Pracros Pediatric Radiology Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author Pierre Mouriquand Pediatric Surgery Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author Pierre-Yves Mure Pediatric Surgery Department, Femme Mère Enfant Hospital–University Hospital of Lyon and University Claude Bernard Lyon 1, Lyon, France More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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