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- W2559574816 abstract "Abstract Abstract 4601 Peripheral T-cell lymphoma (PTCL) is generally characterized by poor prognosis. To determine the role of Hyper-CVAD chemotherapy and autologous stem cell transplantation (ASCT) in PTCL, we retrospectively analyzed the outcomes of 31 patients with PTCL between 1999 and 2009. 15 patients received Hyper-CVAD chemotherapy with 3-year overall survival (OS) of 52.4% and 3-year progression free survival (PFS) of 25.7%. 16 patients received ASCT with 3-year OS of 76.2% and 3-year PFS of 61.3%. There was significant difference in 3-year PFS between the two treatments (P=0.012). Additionally, patients underwent ASCT with elevated LDH, ≥ 2 IPI points and extranodal involvement had a favorable outcome comparing with the ones received Hyper-CVAD chemotherapy. These findings might suggest that ASCT likely offer a durable survival benefit for patients with aggressive peripheral T cell lymphoma. Disclosures: No relevant conflicts of interest to declare." @default.
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- W2559574816 date "2010-11-19" @default.
- W2559574816 modified "2023-09-28" @default.
- W2559574816 title "Comparasion of Hyper-CVAD Chemotherapy with Autologous Stem Cell Transplantation In Patients with Peripheral T Cell Lymphomas: A Single Centre Report." @default.
- W2559574816 doi "https://doi.org/10.1182/blood.v116.21.4601.4601" @default.
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