Matches in SemOpenAlex for { <https://semopenalex.org/work/W2559748136> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2559748136 abstract "Economic barriers preventing commercialization of lignocellulose-toethanol bioconversion processes include the high cost of hydrolytic enzymes. One strategy for cost reduction is to improve the specific activities of cellulases by genetic engineering. However, screening for improved activity typically uses “ideal” cellulosic substrates, and results are not necessarily applicable to more realistic substrates such as pretreated hardwoods and softwoods. For lignocellulosic substrates, nonproductive binding and inactivation of enzymes by the lignin component appear to be important factors limiting catalytic efficiency. A better understanding of these factors could allow engineering of cellulases with improved activity based on reduced enzyme-lignin interaction (“weak lignin-binding cellulases”). To prove this concept, we have shown that naturally occurring cellulases with similar catalytic activity on a model cellulosic substrate can differ significantly in their affinities for lignin. Moreover, although cellulose-binding domains (CBDs) are hydrophobic and probably participate in lignin binding, we show that cellulases lacking CBDs also have a high affinity for lignin, indicating the presence of lignin-binding sites on the catalytic domain." @default.
- W2559748136 created "2016-12-16" @default.
- W2559748136 creator A5029009766 @default.
- W2559748136 creator A5042713406 @default.
- W2559748136 creator A5047209558 @default.
- W2559748136 creator A5053994635 @default.
- W2559748136 creator A5069219291 @default.
- W2559748136 creator A5085025538 @default.
- W2559748136 creator A5089475619 @default.
- W2559748136 date "2005-01-01" @default.
- W2559748136 modified "2023-09-27" @default.
- W2559748136 title "A Novel Approach to Improve Activity of Cellulases for Hydrolysis of Lignocellulosics" @default.
- W2559748136 cites W2131975530 @default.
- W2559748136 hasPublicationYear "2005" @default.
- W2559748136 type Work @default.
- W2559748136 sameAs 2559748136 @default.
- W2559748136 citedByCount "0" @default.
- W2559748136 crossrefType "journal-article" @default.
- W2559748136 hasAuthorship W2559748136A5029009766 @default.
- W2559748136 hasAuthorship W2559748136A5042713406 @default.
- W2559748136 hasAuthorship W2559748136A5047209558 @default.
- W2559748136 hasAuthorship W2559748136A5053994635 @default.
- W2559748136 hasAuthorship W2559748136A5069219291 @default.
- W2559748136 hasAuthorship W2559748136A5085025538 @default.
- W2559748136 hasAuthorship W2559748136A5089475619 @default.
- W2559748136 hasConcept C100544194 @default.
- W2559748136 hasConcept C127413603 @default.
- W2559748136 hasConcept C141603559 @default.
- W2559748136 hasConcept C150903083 @default.
- W2559748136 hasConcept C163283067 @default.
- W2559748136 hasConcept C178790620 @default.
- W2559748136 hasConcept C181199279 @default.
- W2559748136 hasConcept C185592680 @default.
- W2559748136 hasConcept C18903297 @default.
- W2559748136 hasConcept C2777289219 @default.
- W2559748136 hasConcept C2779251873 @default.
- W2559748136 hasConcept C2780074830 @default.
- W2559748136 hasConcept C2781052789 @default.
- W2559748136 hasConcept C528095902 @default.
- W2559748136 hasConcept C55493867 @default.
- W2559748136 hasConcept C86803240 @default.
- W2559748136 hasConcept C94412978 @default.
- W2559748136 hasConceptScore W2559748136C100544194 @default.
- W2559748136 hasConceptScore W2559748136C127413603 @default.
- W2559748136 hasConceptScore W2559748136C141603559 @default.
- W2559748136 hasConceptScore W2559748136C150903083 @default.
- W2559748136 hasConceptScore W2559748136C163283067 @default.
- W2559748136 hasConceptScore W2559748136C178790620 @default.
- W2559748136 hasConceptScore W2559748136C181199279 @default.
- W2559748136 hasConceptScore W2559748136C185592680 @default.
- W2559748136 hasConceptScore W2559748136C18903297 @default.
- W2559748136 hasConceptScore W2559748136C2777289219 @default.
- W2559748136 hasConceptScore W2559748136C2779251873 @default.
- W2559748136 hasConceptScore W2559748136C2780074830 @default.
- W2559748136 hasConceptScore W2559748136C2781052789 @default.
- W2559748136 hasConceptScore W2559748136C528095902 @default.
- W2559748136 hasConceptScore W2559748136C55493867 @default.
- W2559748136 hasConceptScore W2559748136C86803240 @default.
- W2559748136 hasConceptScore W2559748136C94412978 @default.
- W2559748136 hasLocation W25597481361 @default.
- W2559748136 hasOpenAccess W2559748136 @default.
- W2559748136 hasPrimaryLocation W25597481361 @default.
- W2559748136 hasRelatedWork W1013402462 @default.
- W2559748136 hasRelatedWork W1578964909 @default.
- W2559748136 hasRelatedWork W1579365167 @default.
- W2559748136 hasRelatedWork W1588951589 @default.
- W2559748136 hasRelatedWork W196912758 @default.
- W2559748136 hasRelatedWork W1972170812 @default.
- W2559748136 hasRelatedWork W2046768003 @default.
- W2559748136 hasRelatedWork W2132126361 @default.
- W2559748136 hasRelatedWork W2140133474 @default.
- W2559748136 hasRelatedWork W2149237524 @default.
- W2559748136 hasRelatedWork W2350675086 @default.
- W2559748136 hasRelatedWork W2466224833 @default.
- W2559748136 hasRelatedWork W2756313891 @default.
- W2559748136 hasRelatedWork W294793760 @default.
- W2559748136 hasRelatedWork W2950414488 @default.
- W2559748136 hasRelatedWork W2966473533 @default.
- W2559748136 hasRelatedWork W2982675299 @default.
- W2559748136 hasRelatedWork W3186315520 @default.
- W2559748136 hasRelatedWork W3208934838 @default.
- W2559748136 hasRelatedWork W37679245 @default.
- W2559748136 isParatext "false" @default.
- W2559748136 isRetracted "false" @default.
- W2559748136 magId "2559748136" @default.
- W2559748136 workType "article" @default.