FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2559968757> ?p ?o ?g. }

• W2559968757 abstract "Young patients with the endometrial cancerIA who desire to preserve fertility, can select the conservative therapy withprogestin. However, the therapy involves risks of progression and relapse. Weexamined immunohistochemical analyses of phosphatase and tension homolog (PTEN)and p53 expressions to predict the early relapse, and pregnancy and delivery.Twenty women with endometrial cancer, FIGO IA (1988) (FIGO staging wasessentially defined post-surgically), instead of the pathogical specimen beforesurgery without myometrial invasion were estimated by MRI under 40 years atGifu University Hospital, Japan from 1988 to 2009. Patients were treated withmedroxyprogesterone acetate (MPA, 400 - 600 mg/day) for 4 - 10 months, withwhole wall endometrial curettage performed every four weeks. Response to thetherapy, pregnancy, delivery and relapse of disease during follow-up over a72-month period. Immunohistochemical expression of PTEN and p53 was alsoevaluated with pregnancy, delivery and relapse rate. All patients hadpathological complete remissions within 4 - 10 months. Relapse rate was high(60%) in more than 72 months. Immunohistochemical PTEN retain in tumor cellsbefore MPA treatment (8/10) was significant better correlation with pregnancyand delivery rate than of lost cases (1/5) in non-obese women (P < 0.05).Conservative therapy is feasible in carefully selected young women withendometrial cancer without myometrial invasion. However, the relapse rate washigh. In cases who desire to be a pregnant, an earlier infertility treatmentmay be considered especially for PTEN loss especially in nonobese cases." @default.
• W2559968757 created "2016-12-16" @default.
• W2559968757 creator A5001425851 @default.
• W2559968757 creator A5001618823 @default.
• W2559968757 creator A5028027928 @default.
• W2559968757 creator A5039176890 @default.
• W2559968757 creator A5067521653 @default.
• W2559968757 date "2017-01-01" @default.
• W2559968757 modified "2023-09-30" @default.
• W2559968757 title "Conservative Medroxyprogesterone Acetate Therapy in Early Stage of Endometrial Carcinoma Associated with Phosphatase and Tensin Homolog Expression" @default.
• W2559968757 cites W1565532031 @default.
• W2559968757 cites W1593108703 @default.
• W2559968757 cites W1614313922 @default.
• W2559968757 cites W1661647511 @default.
• W2559968757 cites W1911329982 @default.
• W2559968757 cites W1960369368 @default.
• W2559968757 cites W1968907388 @default.
• W2559968757 cites W1973733252 @default.
• W2559968757 cites W1975022926 @default.
• W2559968757 cites W1981344902 @default.
• W2559968757 cites W1993983335 @default.
• W2559968757 cites W2005404300 @default.
• W2559968757 cites W2006680628 @default.
• W2559968757 cites W2012908122 @default.
• W2559968757 cites W2030813163 @default.
• W2559968757 cites W2041606368 @default.
• W2559968757 cites W2047111383 @default.
• W2559968757 cites W2056416591 @default.
• W2559968757 cites W2060221114 @default.
• W2559968757 cites W2067751798 @default.
• W2559968757 cites W2069547854 @default.
• W2559968757 cites W2106676074 @default.
• W2559968757 cites W2111109989 @default.
• W2559968757 cites W2116755440 @default.
• W2559968757 cites W2132279561 @default.
• W2559968757 cites W2135919065 @default.
• W2559968757 cites W2136602069 @default.
• W2559968757 cites W2136627812 @default.
• W2559968757 cites W2146896519 @default.
• W2559968757 cites W2156637804 @default.
• W2559968757 cites W2161640106 @default.
• W2559968757 cites W2164108689 @default.
• W2559968757 cites W2167264978 @default.
• W2559968757 cites W2330832491 @default.
• W2559968757 cites W2499258379 @default.
• W2559968757 doi "https://doi.org/10.4236/ojpathology.2017.71001" @default.
• W2559968757 hasPublicationYear "2017" @default.
• W2559968757 type Work @default.
• W2559968757 sameAs 2559968757 @default.
• W2559968757 citedByCount "0" @default.
• W2559968757 crossrefType "journal-article" @default.
• W2559968757 hasAuthorship W2559968757A5001425851 @default.
• W2559968757 hasAuthorship W2559968757A5001618823 @default.
• W2559968757 hasAuthorship W2559968757A5028027928 @default.
• W2559968757 hasAuthorship W2559968757A5039176890 @default.
• W2559968757 hasAuthorship W2559968757A5067521653 @default.
• W2559968757 hasBestOaLocation W25599687571 @default.
• W2559968757 hasConcept C121608353 @default.
• W2559968757 hasConcept C126322002 @default.
• W2559968757 hasConcept C143998085 @default.
• W2559968757 hasConcept C146357865 @default.
• W2559968757 hasConcept C151730666 @default.
• W2559968757 hasConcept C190283241 @default.
• W2559968757 hasConcept C204232928 @default.
• W2559968757 hasConcept C207886595 @default.
• W2559968757 hasConcept C2776306185 @default.
• W2559968757 hasConcept C2776607906 @default.
• W2559968757 hasConcept C2777088508 @default.
• W2559968757 hasConcept C2777164284 @default.
• W2559968757 hasConcept C2777546739 @default.
• W2559968757 hasConcept C2777609662 @default.
• W2559968757 hasConcept C2779234561 @default.
• W2559968757 hasConcept C2779549131 @default.
• W2559968757 hasConcept C29456083 @default.
• W2559968757 hasConcept C54355233 @default.
• W2559968757 hasConcept C55493867 @default.
• W2559968757 hasConcept C71924100 @default.
• W2559968757 hasConcept C86554907 @default.
• W2559968757 hasConcept C86803240 @default.
• W2559968757 hasConceptScore W2559968757C121608353 @default.
• W2559968757 hasConceptScore W2559968757C126322002 @default.
• W2559968757 hasConceptScore W2559968757C143998085 @default.
• W2559968757 hasConceptScore W2559968757C146357865 @default.
• W2559968757 hasConceptScore W2559968757C151730666 @default.
• W2559968757 hasConceptScore W2559968757C190283241 @default.
• W2559968757 hasConceptScore W2559968757C204232928 @default.
• W2559968757 hasConceptScore W2559968757C207886595 @default.
• W2559968757 hasConceptScore W2559968757C2776306185 @default.
• W2559968757 hasConceptScore W2559968757C2776607906 @default.
• W2559968757 hasConceptScore W2559968757C2777088508 @default.
• W2559968757 hasConceptScore W2559968757C2777164284 @default.
• W2559968757 hasConceptScore W2559968757C2777546739 @default.
• W2559968757 hasConceptScore W2559968757C2777609662 @default.
• W2559968757 hasConceptScore W2559968757C2779234561 @default.
• W2559968757 hasConceptScore W2559968757C2779549131 @default.
• W2559968757 hasConceptScore W2559968757C29456083 @default.
• W2559968757 hasConceptScore W2559968757C54355233 @default.
• W2559968757 hasConceptScore W2559968757C55493867 @default.
• W2559968757 hasConceptScore W2559968757C71924100 @default.
• W2559968757 hasConceptScore W2559968757C86554907 @default.

• next