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- W255998512 abstract "Chromosome aberration data obtained for various types of mammalian cells after exposure to low and high LET clearly demonstrate [1] the differences in the energy deposition pattern of both radiation qualities. In the study reported here the distribution of chromosome aberrations observed in human peripheral blood lymphocytes at the first mitosis after exposure to 900 MeV/u Fe (LET=155keV/μm) ions was analyzed and compared to the effects of 250 kV X-rays [1]. After X-ray exposure the distribution of aberrations among cells was well characterized by a Poisson distribution, reflecting a simple random distribution of damages as expected according to the homogeneous pattern of energy distribution. On the contrary, after high LET exposure, the distribution of aberrations reflected the microscopic inhomogeneity of energy depositions (see Fig.1). Moreover, since in the experiments first cycle metaphase cells were collected at several sampling times, additionally insights into high and low LET induced cell cycle delays were obtained. If par-" @default.
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- W255998512 date "2006-01-01" @default.
- W255998512 modified "2023-09-26" @default.
- W255998512 title "Effect of lET and track structure on the statistical analysis of chromosome aberrations: Use of the convoluted Poisson-Neyman distribution." @default.
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