FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2560015040> ?p ?o ?g. }

• W2560015040 endingPage "2586" @default.
• W2560015040 startingPage "2575" @default.
• W2560015040 abstract "Increasing evidence suggests that microRNA-101 (miR-101) is involved in the progression of various human cancers, including papillary thyroid carcinoma (PTC). However, the biological functions of miR-101 and underlying molecular mechanisms in PTC remain largely unknown. In this study, we demonstrated that miR-101 underexpression in PTC tissue was associated with lymph node metastasis and poor prognosis of PTC patients. MiR-101 reduced PTC cell proliferation, apoptosis resistance, and invasion. Ubiquitin-specific protease 22 (USP22) was confirmed as a direct target of miR-101. USP22 restoration attenuated the inhibitory effects of miR-101 on PTC malignant traits in vitro. In vivo, miR-101 overexpression or USP22 depletion reduced the tumorigenesis of PTC. Overall, our findings provide new insight into the mechanism of PTC inhibition by miR-101, suggesting the potential of miR-101 as a therapeutic target in PTC patients." @default.
• W2560015040 created "2016-12-16" @default.
• W2560015040 creator A5001704075 @default.
• W2560015040 creator A5002607371 @default.
• W2560015040 creator A5015583741 @default.
• W2560015040 creator A5018508891 @default.
• W2560015040 creator A5019574552 @default.
• W2560015040 creator A5046277098 @default.
• W2560015040 creator A5050619645 @default.
• W2560015040 creator A5056755738 @default.
• W2560015040 creator A5063620518 @default.
• W2560015040 creator A5070944105 @default.
• W2560015040 creator A5079297024 @default.
• W2560015040 creator A5084688409 @default.
• W2560015040 creator A5089620708 @default.
• W2560015040 date "2016-01-01" @default.
• W2560015040 modified "2023-09-27" @default.
• W2560015040 title "MiR-101 targets USP22 to inhibit the tumorigenesis of papillary thyroid carcinoma." @default.
• W2560015040 cites W144423133 @default.
• W2560015040 cites W1590634950 @default.
• W2560015040 cites W1974033399 @default.
• W2560015040 cites W1975694453 @default.
• W2560015040 cites W1985457111 @default.
• W2560015040 cites W1998263705 @default.
• W2560015040 cites W1999942581 @default.
• W2560015040 cites W2003428814 @default.
• W2560015040 cites W2004095765 @default.
• W2560015040 cites W2020031294 @default.
• W2560015040 cites W2023620453 @default.
• W2560015040 cites W2026583544 @default.
• W2560015040 cites W2037027150 @default.
• W2560015040 cites W2062873714 @default.
• W2560015040 cites W2069752065 @default.
• W2560015040 cites W2076196135 @default.
• W2560015040 cites W2076583198 @default.
• W2560015040 cites W2087367170 @default.
• W2560015040 cites W2092846304 @default.
• W2560015040 cites W2100932663 @default.
• W2560015040 cites W2124681173 @default.
• W2560015040 cites W2143815536 @default.
• W2560015040 cites W2144287208 @default.
• W2560015040 cites W2146445411 @default.
• W2560015040 cites W2149139293 @default.
• W2560015040 cites W2194227124 @default.
• W2560015040 cites W2344533816 @default.
• W2560015040 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5126274" @default.
• W2560015040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27904772" @default.
• W2560015040 hasPublicationYear "2016" @default.
• W2560015040 type Work @default.
• W2560015040 sameAs 2560015040 @default.
• W2560015040 citedByCount "15" @default.
• W2560015040 countsByYear W25600150402017 @default.
• W2560015040 countsByYear W25600150402018 @default.
• W2560015040 countsByYear W25600150402019 @default.
• W2560015040 countsByYear W25600150402021 @default.
• W2560015040 countsByYear W25600150402022 @default.
• W2560015040 countsByYear W25600150402023 @default.
• W2560015040 crossrefType "journal-article" @default.
• W2560015040 hasAuthorship W2560015040A5001704075 @default.
• W2560015040 hasAuthorship W2560015040A5002607371 @default.
• W2560015040 hasAuthorship W2560015040A5015583741 @default.
• W2560015040 hasAuthorship W2560015040A5018508891 @default.
• W2560015040 hasAuthorship W2560015040A5019574552 @default.
• W2560015040 hasAuthorship W2560015040A5046277098 @default.
• W2560015040 hasAuthorship W2560015040A5050619645 @default.
• W2560015040 hasAuthorship W2560015040A5056755738 @default.
• W2560015040 hasAuthorship W2560015040A5063620518 @default.
• W2560015040 hasAuthorship W2560015040A5070944105 @default.
• W2560015040 hasAuthorship W2560015040A5079297024 @default.
• W2560015040 hasAuthorship W2560015040A5084688409 @default.
• W2560015040 hasAuthorship W2560015040A5089620708 @default.
• W2560015040 hasConcept C104317684 @default.
• W2560015040 hasConcept C121608353 @default.
• W2560015040 hasConcept C126322002 @default.
• W2560015040 hasConcept C145059251 @default.
• W2560015040 hasConcept C190283241 @default.
• W2560015040 hasConcept C202751555 @default.
• W2560015040 hasConcept C207001950 @default.
• W2560015040 hasConcept C2779013556 @default.
• W2560015040 hasConcept C2993294228 @default.
• W2560015040 hasConcept C502942594 @default.
• W2560015040 hasConcept C526584372 @default.
• W2560015040 hasConcept C54355233 @default.
• W2560015040 hasConcept C55493867 @default.
• W2560015040 hasConcept C555283112 @default.
• W2560015040 hasConcept C62112901 @default.
• W2560015040 hasConcept C71924100 @default.
• W2560015040 hasConcept C86803240 @default.
• W2560015040 hasConceptScore W2560015040C104317684 @default.
• W2560015040 hasConceptScore W2560015040C121608353 @default.
• W2560015040 hasConceptScore W2560015040C126322002 @default.
• W2560015040 hasConceptScore W2560015040C145059251 @default.
• W2560015040 hasConceptScore W2560015040C190283241 @default.
• W2560015040 hasConceptScore W2560015040C202751555 @default.
• W2560015040 hasConceptScore W2560015040C207001950 @default.
• W2560015040 hasConceptScore W2560015040C2779013556 @default.
• W2560015040 hasConceptScore W2560015040C2993294228 @default.
• W2560015040 hasConceptScore W2560015040C502942594 @default.

• next