FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2560103313> ?p ?o ?g. }

• W2560103313 endingPage "598" @default.
• W2560103313 startingPage "588" @default.
• W2560103313 abstract "In Brief BACKGROUND: To reduce head movement during resting state functional magnetic resonance imaging, post-coma patients with disorders of consciousness (DOC) are frequently sedated with propofol. However, little is known about the effects of this sedation on the brain connectivity patterns in the damaged brain essential for differential diagnosis. In this study, we aimed to assess these effects. METHODS: Using resting state functional magnetic resonance imaging 3T data obtained over several years of scanning patients for diagnostic and research purposes, we employed a seed-based approach to examine resting state connectivity in higher-order (default mode, bilateral external control, and salience) and lower-order (auditory, sensorimotor, and visual) resting state networks and connectivity with the thalamus, in 20 healthy unsedated controls, 8 unsedated patients with DOC, and 8 patients with DOC sedated with propofol. The DOC groups were matched for age at onset, etiology, time spent in DOC, diagnosis, standardized behavioral assessment scores, movement intensities, and pattern of structural brain injury (as assessed with T1-based voxel-based morphometry). RESULTS: DOC were associated with severely impaired resting state network connectivity in all but the visual network. Thalamic connectivity to higher-order network regions was also reduced. Propofol administration to patients was associated with minor further decreases in thalamic and insular connectivity. CONCLUSIONS: Our findings indicate that connectivity decreases associated with propofol sedation, involving the thalamus and insula, are relatively small compared with those already caused by DOC-associated structural brain injury. Nonetheless, given the known importance of the thalamus in brain arousal, its disruption could well reflect the diminished movement obtained in these patients. However, more research is needed on this topic to fully address the research question. Published ahead of print December 8, 2016." @default.
• W2560103313 created "2016-12-16" @default.
• W2560103313 creator A5001943118 @default.
• W2560103313 creator A5009690578 @default.
• W2560103313 creator A5016084069 @default.
• W2560103313 creator A5021017127 @default.
• W2560103313 creator A5024625204 @default.
• W2560103313 creator A5028331198 @default.
• W2560103313 creator A5028616268 @default.
• W2560103313 creator A5042265881 @default.
• W2560103313 creator A5047951085 @default.
• W2560103313 creator A5049400483 @default.
• W2560103313 creator A5059273717 @default.
• W2560103313 creator A5061379701 @default.
• W2560103313 creator A5062003959 @default.
• W2560103313 creator A5072188433 @default.
• W2560103313 creator A5073516200 @default.
• W2560103313 creator A5088346225 @default.
• W2560103313 date "2017-02-01" @default.
• W2560103313 modified "2023-10-16" @default.
• W2560103313 title "Sedation of Patients With Disorders of Consciousness During Neuroimaging" @default.
• W2560103313 cites W1536122414 @default.
• W2560103313 cites W1596614913 @default.
• W2560103313 cites W1963506488 @default.
• W2560103313 cites W1971853395 @default.
• W2560103313 cites W1972524658 @default.
• W2560103313 cites W1985408596 @default.
• W2560103313 cites W1985624905 @default.
• W2560103313 cites W1985673618 @default.
• W2560103313 cites W1986387796 @default.
• W2560103313 cites W1990134753 @default.
• W2560103313 cites W1993787537 @default.
• W2560103313 cites W1997260622 @default.
• W2560103313 cites W1998824590 @default.
• W2560103313 cites W1999830133 @default.
• W2560103313 cites W2002293846 @default.
• W2560103313 cites W2002923643 @default.
• W2560103313 cites W2003197739 @default.
• W2560103313 cites W2012249671 @default.
• W2560103313 cites W2017762614 @default.
• W2560103313 cites W2033349308 @default.
• W2560103313 cites W2046189265 @default.
• W2560103313 cites W2047189453 @default.
• W2560103313 cites W2048265343 @default.
• W2560103313 cites W2049325056 @default.
• W2560103313 cites W2050597556 @default.
• W2560103313 cites W2055172775 @default.
• W2560103313 cites W2064433584 @default.
• W2560103313 cites W2068900341 @default.
• W2560103313 cites W2072309592 @default.
• W2560103313 cites W2081716263 @default.
• W2560103313 cites W2085374253 @default.
• W2560103313 cites W2090957966 @default.
• W2560103313 cites W2093972428 @default.
• W2560103313 cites W2097792392 @default.
• W2560103313 cites W2106243645 @default.
• W2560103313 cites W2107632000 @default.
• W2560103313 cites W2110447288 @default.
• W2560103313 cites W2110954320 @default.
• W2560103313 cites W2112639978 @default.
• W2560103313 cites W2114294544 @default.
• W2560103313 cites W2116658855 @default.
• W2560103313 cites W2123477708 @default.
• W2560103313 cites W2124163668 @default.
• W2560103313 cites W2126155630 @default.
• W2560103313 cites W2126349398 @default.
• W2560103313 cites W2126602481 @default.
• W2560103313 cites W2127129724 @default.
• W2560103313 cites W2128126559 @default.
• W2560103313 cites W2132787089 @default.
• W2560103313 cites W2134641746 @default.
• W2560103313 cites W2142794733 @default.
• W2560103313 cites W2145403933 @default.
• W2560103313 cites W2147914276 @default.
• W2560103313 cites W2150682709 @default.
• W2560103313 cites W2150967988 @default.
• W2560103313 cites W2155298532 @default.
• W2560103313 cites W2157280093 @default.
• W2560103313 cites W2157838041 @default.
• W2560103313 cites W2161992525 @default.
• W2560103313 cites W2167882009 @default.
• W2560103313 cites W2168095862 @default.
• W2560103313 cites W2168575964 @default.
• W2560103313 cites W2169345238 @default.
• W2560103313 cites W2218427460 @default.
• W2560103313 cites W2268985877 @default.
• W2560103313 cites W2293150817 @default.
• W2560103313 cites W2312504587 @default.
• W2560103313 cites W2552492215 @default.
• W2560103313 doi "https://doi.org/10.1213/ane.0000000000001721" @default.
• W2560103313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27941576" @default.
• W2560103313 hasPublicationYear "2017" @default.
• W2560103313 type Work @default.
• W2560103313 sameAs 2560103313 @default.
• W2560103313 citedByCount "37" @default.
• W2560103313 countsByYear W25601033132017 @default.
• W2560103313 countsByYear W25601033132018 @default.
• W2560103313 countsByYear W25601033132019 @default.

• next