FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2560105088> ?p ?o ?g. }

• W2560105088 endingPage "81" @default.
• W2560105088 startingPage "73" @default.
• W2560105088 abstract "Summary Pulmonary embolism (PE) is a relatively common cardiovascular emergency, though its exact incidence is difficult to assess. Accurate diagnosis is critical because of the high 30-day mortality in patients in whom the diagnosis is missed on admission. Doubt for PE is often raised by the presence of risk factors for venous thromboembolism (VTE), which are categorized into inherited and acquired. Among these, the importance of inherited/genetic thrombophilic factors is increasingly recognized. The most frequent markers of inherited thrombophilia are Factor V Leiden (FVL) and G2021OA prothrombin gene mutation. Among the inherited factors causal to thrombophilia, the C677T variant in methylentetrahydrofolate reductase (MTHFR) gene as well as factors like P1A1/P1A2 polymorphism in platelet glycoprotein Ilb/IIIa (P1A2) and hypofibrinolytic polymorphism 4G/4G in PAI-1 gene are discussed with controversial results. In our study, thrombophilic and hypofibrinolytic genetic variants were identified in 54.2% of 115 patients with PE. The most common significant genetic defects were FVL- 16.5% in patients versus 6.2% in controls (OR=3.102; p=0.05), G20210A PT 5.7% versus 2.1% (OR=2.983; p>0.05). P1A2 was found in 27.3% patients versus 19.9% in controls (OR= 1.523, p>0.05) and PAM 27.8% versus 22.6% (OR =1.501 p>0.05). MTHFR C677T carriage was inverse: 6.7% in patients versus 13.4% in controls. (OR=0.461 p=0.05). Of all the patients studied, 15.65% had a history of recurrent embolic incidents. The risk of recurrence was higher for the carriers of FVL and G20210A prothrombin gene mutation. The association between carriage of thrombophilic genetic factor and the early onset of the first embolic episode was found in the patients with PE. The awareness of risk factors and risk stratification is a critical issue in treatment and prevention policy. Preventive measures should be taken in particular medical conditions." @default.
• W2560105088 created "2016-12-16" @default.
• W2560105088 creator A5033807588 @default.
• W2560105088 creator A5046099060 @default.
• W2560105088 creator A5052881397 @default.
• W2560105088 creator A5060705353 @default.
• W2560105088 creator A5077388728 @default.
• W2560105088 creator A5078295715 @default.
• W2560105088 creator A5083265925 @default.
• W2560105088 creator A5091726862 @default.
• W2560105088 date "2013-12-01" @default.
• W2560105088 modified "2023-10-14" @default.
• W2560105088 title "Predisposition to Thrombophilia and Hypofibrinolysis in Pulmonary Embolism: Analysis of Inherited Factors" @default.
• W2560105088 cites W1445101152 @default.
• W2560105088 cites W1531281563 @default.
• W2560105088 cites W166555176 @default.
• W2560105088 cites W1950876602 @default.
• W2560105088 cites W1978368046 @default.
• W2560105088 cites W1985217863 @default.
• W2560105088 cites W1987799813 @default.
• W2560105088 cites W1996233154 @default.
• W2560105088 cites W1997402802 @default.
• W2560105088 cites W2016492461 @default.
• W2560105088 cites W2020858579 @default.
• W2560105088 cites W2032021142 @default.
• W2560105088 cites W2047480444 @default.
• W2560105088 cites W2049381991 @default.
• W2560105088 cites W2052703878 @default.
• W2560105088 cites W2054476774 @default.
• W2560105088 cites W2074435426 @default.
• W2560105088 cites W2080396603 @default.
• W2560105088 cites W2083657176 @default.
• W2560105088 cites W2085356598 @default.
• W2560105088 cites W2090735669 @default.
• W2560105088 cites W2093766743 @default.
• W2560105088 cites W2098660021 @default.
• W2560105088 cites W2101371933 @default.
• W2560105088 cites W2102535207 @default.
• W2560105088 cites W2110134277 @default.
• W2560105088 cites W2114814128 @default.
• W2560105088 cites W2130771157 @default.
• W2560105088 cites W2157876594 @default.
• W2560105088 cites W2172179400 @default.
• W2560105088 cites W2316248832 @default.
• W2560105088 cites W2329867113 @default.
• W2560105088 cites W2340351677 @default.
• W2560105088 cites W4232809868 @default.
• W2560105088 cites W4293857995 @default.
• W2560105088 cites W4327849098 @default.
• W2560105088 doi "https://doi.org/10.1515/jbcr-2015-0105" @default.
• W2560105088 hasPublicationYear "2013" @default.
• W2560105088 type Work @default.
• W2560105088 sameAs 2560105088 @default.
• W2560105088 citedByCount "1" @default.
• W2560105088 countsByYear W25601050882015 @default.
• W2560105088 crossrefType "journal-article" @default.
• W2560105088 hasAuthorship W2560105088A5033807588 @default.
• W2560105088 hasAuthorship W2560105088A5046099060 @default.
• W2560105088 hasAuthorship W2560105088A5052881397 @default.
• W2560105088 hasAuthorship W2560105088A5060705353 @default.
• W2560105088 hasAuthorship W2560105088A5077388728 @default.
• W2560105088 hasAuthorship W2560105088A5078295715 @default.
• W2560105088 hasAuthorship W2560105088A5083265925 @default.
• W2560105088 hasAuthorship W2560105088A5091726862 @default.
• W2560105088 hasBestOaLocation W25601050881 @default.
• W2560105088 hasConcept C104317684 @default.
• W2560105088 hasConcept C126322002 @default.
• W2560105088 hasConcept C180754005 @default.
• W2560105088 hasConcept C2776046644 @default.
• W2560105088 hasConcept C2776265017 @default.
• W2560105088 hasConcept C2777175894 @default.
• W2560105088 hasConcept C2780011451 @default.
• W2560105088 hasConcept C2780842393 @default.
• W2560105088 hasConcept C2780868729 @default.
• W2560105088 hasConcept C43563269 @default.
• W2560105088 hasConcept C54355233 @default.
• W2560105088 hasConcept C71924100 @default.
• W2560105088 hasConcept C86803240 @default.
• W2560105088 hasConcept C90924648 @default.
• W2560105088 hasConceptScore W2560105088C104317684 @default.
• W2560105088 hasConceptScore W2560105088C126322002 @default.
• W2560105088 hasConceptScore W2560105088C180754005 @default.
• W2560105088 hasConceptScore W2560105088C2776046644 @default.
• W2560105088 hasConceptScore W2560105088C2776265017 @default.
• W2560105088 hasConceptScore W2560105088C2777175894 @default.
• W2560105088 hasConceptScore W2560105088C2780011451 @default.
• W2560105088 hasConceptScore W2560105088C2780842393 @default.
• W2560105088 hasConceptScore W2560105088C2780868729 @default.
• W2560105088 hasConceptScore W2560105088C43563269 @default.
• W2560105088 hasConceptScore W2560105088C54355233 @default.
• W2560105088 hasConceptScore W2560105088C71924100 @default.
• W2560105088 hasConceptScore W2560105088C86803240 @default.
• W2560105088 hasConceptScore W2560105088C90924648 @default.
• W2560105088 hasIssue "2" @default.
• W2560105088 hasLocation W25601050881 @default.
• W2560105088 hasOpenAccess W2560105088 @default.
• W2560105088 hasPrimaryLocation W25601050881 @default.
• W2560105088 hasRelatedWork W1669245089 @default.

• next