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• W2560359096 abstract "Herpesvirus host cells are defined by their susceptibility to productive or latent infection. Herpesvirus host cells contribute to navigation of viruses through the infected host, either directly as vehicles or indirectly by shaping the glycoprotein content of viral envelopes. Herpesviruses can manipulate their host cells by changing their differentiation status. Herpesviruses stand out by a highly redundant equipment with regulatory proteins or noncoding RNAs. This redundancy stands in the way of clearing a herpesvirus infection. The development of new antiherpesviral drugs or vaccines, and the application of herpesviruses as oncolytic agents, vaccine- or gene-therapy vectors depends on understanding interactions between viral and host cell factors. During a long history of coevolution, herpesviruses have reached a fine-tuned balance with their hosts, allowing them to successfully persist and spread to new hosts without causing too much damage. Only under certain circumstances, as in neonates or immunocompromised individuals, they may cause serious diseases. The delicate balance between herpesviruses and their hosts results from interactions of a great variety of viral and cellular factors which together shape the tropism for a particular host, tissue, or cell. Understanding these interactions will provide insight into the viral life cycle and cell biology in general. Moreover, it will also facilitate comprehension of herpesvirus pathogenesis, enabling the development of new strategies to combat herpesviruses in cases where they cause disease. During a long history of coevolution, herpesviruses have reached a fine-tuned balance with their hosts, allowing them to successfully persist and spread to new hosts without causing too much damage. Only under certain circumstances, as in neonates or immunocompromised individuals, they may cause serious diseases. The delicate balance between herpesviruses and their hosts results from interactions of a great variety of viral and cellular factors which together shape the tropism for a particular host, tissue, or cell. Understanding these interactions will provide insight into the viral life cycle and cell biology in general. Moreover, it will also facilitate comprehension of herpesvirus pathogenesis, enabling the development of new strategies to combat herpesviruses in cases where they cause disease. a site-specific recombination system, consisting of the enzyme Cre recombinase and a pair of short target sequences, called loxP sites. Cre catalyzes DNA recombination between the loxP sites, and recombination between a pair of directly repeated loxP sites results in the deletion of the intervening DNA (the so-called floxed sequence). an analytical technique that ionizes chemical species and sorts the ions based on their mass-to-charge ratio. large-scale study of proteins. a biological process in which RNA molecules inhibit gene expression. stable isotope labeling with amino acids in cell culture. The technique is based on mass spectrometry that detects differences in protein abundance among samples using nonradioactive isotopic labeling. Cells are differentially labeled by growing them in medium either containing normal amino acids or amino acids labeled with stable, nonradioactive heavy isotopes. Metabolic incorporation of the amino acids into proteins results in a mass shift of the corresponding peptides. When two samples are combined, the relative protein abundance is reflected by the ratio of peak intensities in the mass spectrum. a combination of flow cytometry and mass spectrometry, also called cytometry by time-of-flight (CyTOF). a purification technique for studying protein–protein interactions, applying a protein with a designed tag, the TAP tag. the capacity of a virus to infect or damage specific cells, tissues, or species." @default.
• W2560359096 created "2016-12-16" @default.
• W2560359096 creator A5009844097 @default.
• W2560359096 creator A5024093369 @default.
• W2560359096 creator A5082265210 @default.
• W2560359096 date "2017-03-01" @default.
• W2560359096 modified "2023-10-04" @default.
• W2560359096 title "Herpesviruses and Their Host Cells: A Successful Liaison" @default.
• W2560359096 cites W1427826206 @default.
• W2560359096 cites W1535888909 @default.
• W2560359096 cites W1557213989 @default.
• W2560359096 cites W1629500030 @default.
• W2560359096 cites W1730409572 @default.
• W2560359096 cites W1750656282 @default.
• W2560359096 cites W1956111474 @default.
• W2560359096 cites W1963112395 @default.
• W2560359096 cites W1965004882 @default.
• W2560359096 cites W1966071032 @default.
• W2560359096 cites W1974572224 @default.
• W2560359096 cites W1977249590 @default.
• W2560359096 cites W1979921905 @default.
• W2560359096 cites W1982340122 @default.
• W2560359096 cites W1982666150 @default.
• W2560359096 cites W1984050877 @default.
• W2560359096 cites W1988998505 @default.
• W2560359096 cites W1991443797 @default.
• W2560359096 cites W1991457448 @default.
• W2560359096 cites W1993913284 @default.
• W2560359096 cites W1995177381 @default.
• W2560359096 cites W1998318447 @default.
• W2560359096 cites W2003704751 @default.
• W2560359096 cites W2007437931 @default.
• W2560359096 cites W2014681718 @default.
• W2560359096 cites W2015035889 @default.
• W2560359096 cites W2023009580 @default.
• W2560359096 cites W2025577778 @default.
• W2560359096 cites W2025692636 @default.
• W2560359096 cites W2031176852 @default.
• W2560359096 cites W2035176951 @default.
• W2560359096 cites W2038591366 @default.
• W2560359096 cites W2041016435 @default.
• W2560359096 cites W2041805272 @default.
• W2560359096 cites W2041999503 @default.
• W2560359096 cites W2042004955 @default.
• W2560359096 cites W2043486017 @default.
• W2560359096 cites W2043919474 @default.
• W2560359096 cites W2047097279 @default.
• W2560359096 cites W2049596485 @default.
• W2560359096 cites W2052378894 @default.
• W2560359096 cites W2058972859 @default.
• W2560359096 cites W2066083338 @default.
• W2560359096 cites W2079014709 @default.
• W2560359096 cites W2085388950 @default.
• W2560359096 cites W2088591999 @default.
• W2560359096 cites W2092894964 @default.
• W2560359096 cites W2095307580 @default.
• W2560359096 cites W2095429824 @default.
• W2560359096 cites W2095560405 @default.
• W2560359096 cites W2098044274 @default.
• W2560359096 cites W2105501854 @default.
• W2560359096 cites W2106230667 @default.
• W2560359096 cites W2110940073 @default.
• W2560359096 cites W2111370529 @default.
• W2560359096 cites W2111725944 @default.
• W2560359096 cites W2114890741 @default.
• W2560359096 cites W2115834887 @default.
• W2560359096 cites W2118382148 @default.
• W2560359096 cites W2120767499 @default.
• W2560359096 cites W2126588758 @default.
• W2560359096 cites W2128715200 @default.
• W2560359096 cites W2132151944 @default.
• W2560359096 cites W2137735741 @default.
• W2560359096 cites W2138987143 @default.
• W2560359096 cites W2142485337 @default.
• W2560359096 cites W2145766077 @default.
• W2560359096 cites W2146947673 @default.
• W2560359096 cites W2150241121 @default.
• W2560359096 cites W2151876257 @default.
• W2560359096 cites W2152044952 @default.
• W2560359096 cites W2153572732 @default.
• W2560359096 cites W2154013025 @default.
• W2560359096 cites W2154539817 @default.
• W2560359096 cites W2155478615 @default.
• W2560359096 cites W2157605131 @default.
• W2560359096 cites W2166896254 @default.
• W2560359096 cites W2170890136 @default.
• W2560359096 cites W2174064529 @default.
• W2560359096 cites W2176701153 @default.
• W2560359096 cites W2178984934 @default.
• W2560359096 cites W2196734217 @default.
• W2560359096 cites W2211415647 @default.
• W2560359096 cites W2225275485 @default.
• W2560359096 cites W2226553831 @default.
• W2560359096 cites W2239321195 @default.
• W2560359096 cites W2258308895 @default.
• W2560359096 cites W2259398295 @default.
• W2560359096 cites W2261633018 @default.
• W2560359096 cites W2264201737 @default.

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