FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2560392011> ?p ?o ?g. }

• W2560392011 endingPage "193" @default.
• W2560392011 startingPage "187" @default.
• W2560392011 abstract "In this study, lentivirus-mediated RNA interference (RNAi) was applied to inhibit latent membrane protein 2A (LMP2A) gene expression, in order to explore the effects of LMP2A silencing on the growth of an Epstein‑Barr virus‑associated gastric carcinoma (EBVaGC) cell line in vitro. Lentivirus-mediated RNAi technology was employed to specifically knock down the LMP2A gene in the EBV‑positive gastric carcinoma cell line GT38. After infection, reverse transcription‑quantitative polymerase chain reaction, western blotting, flow cytometry and colony formation assays were conducted to evaluate the expression of LMP2A and the biological behavior of the GT38 cell line in vitro. The results showed that the expression of the LMP2A gene was clearly downregulated in the infected cells, which indicated that a highly efficient and stable lentivirus vector was successfully constructed. In the GT38 cells in which the expression of LMP2A was downregulated, the proliferation and colony formation of the cells was significantly inhibited. In addition, it was found that the cell cycle of the GT38 cells was arrested in the G0/G1 phase and the apoptosis rate was increased. These results indicate that lentivirus‑mediated RNAi knockdown of LMP2A inhibits the growth of the EBVaGC cell line GT38 in vitro, and suggests that LMP2A is a potential target for gene therapy in the treatment of EBVaGC." @default.
• W2560392011 created "2016-12-16" @default.
• W2560392011 creator A5007120720 @default.
• W2560392011 creator A5008470213 @default.
• W2560392011 creator A5014519339 @default.
• W2560392011 creator A5032882351 @default.
• W2560392011 creator A5033764099 @default.
• W2560392011 creator A5035211521 @default.
• W2560392011 creator A5064328273 @default.
• W2560392011 creator A5073609374 @default.
• W2560392011 date "2016-12-05" @default.
• W2560392011 modified "2023-10-01" @default.
• W2560392011 title "Lentivirus-mediated RNAi knockdown of LMP2A inhibits the growth of the Epstein-Barr-associated gastric carcinoma cell line GT38 in vitro" @default.
• W2560392011 cites W1647075334 @default.
• W2560392011 cites W2001699583 @default.
• W2560392011 cites W2002223549 @default.
• W2560392011 cites W2006646444 @default.
• W2560392011 cites W2009173868 @default.
• W2560392011 cites W2012913175 @default.
• W2560392011 cites W2019411198 @default.
• W2560392011 cites W2032548081 @default.
• W2560392011 cites W2035401671 @default.
• W2560392011 cites W2074896334 @default.
• W2560392011 cites W2094751554 @default.
• W2560392011 cites W2099334895 @default.
• W2560392011 cites W2107277218 @default.
• W2560392011 cites W2109123523 @default.
• W2560392011 cites W2114776909 @default.
• W2560392011 cites W2135740800 @default.
• W2560392011 cites W2146007990 @default.
• W2560392011 cites W2150330606 @default.
• W2560392011 cites W2150357985 @default.
• W2560392011 cites W2156523607 @default.
• W2560392011 cites W2159327683 @default.
• W2560392011 cites W2164492333 @default.
• W2560392011 cites W2164584921 @default.
• W2560392011 cites W2167058139 @default.
• W2560392011 cites W2192080449 @default.
• W2560392011 doi "https://doi.org/10.3892/etm.2016.3954" @default.
• W2560392011 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5245129" @default.
• W2560392011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28123488" @default.
• W2560392011 hasPublicationYear "2016" @default.
• W2560392011 type Work @default.
• W2560392011 sameAs 2560392011 @default.
• W2560392011 citedByCount "13" @default.
• W2560392011 countsByYear W25603920112018 @default.
• W2560392011 countsByYear W25603920112019 @default.
• W2560392011 countsByYear W25603920112020 @default.
• W2560392011 countsByYear W25603920112021 @default.
• W2560392011 countsByYear W25603920112022 @default.
• W2560392011 countsByYear W25603920112023 @default.
• W2560392011 crossrefType "journal-article" @default.
• W2560392011 hasAuthorship W2560392011A5007120720 @default.
• W2560392011 hasAuthorship W2560392011A5008470213 @default.
• W2560392011 hasAuthorship W2560392011A5014519339 @default.
• W2560392011 hasAuthorship W2560392011A5032882351 @default.
• W2560392011 hasAuthorship W2560392011A5033764099 @default.
• W2560392011 hasAuthorship W2560392011A5035211521 @default.
• W2560392011 hasAuthorship W2560392011A5064328273 @default.
• W2560392011 hasAuthorship W2560392011A5073609374 @default.
• W2560392011 hasBestOaLocation W25603920111 @default.
• W2560392011 hasConcept C104317684 @default.
• W2560392011 hasConcept C119056186 @default.
• W2560392011 hasConcept C1491633281 @default.
• W2560392011 hasConcept C153911025 @default.
• W2560392011 hasConcept C159047783 @default.
• W2560392011 hasConcept C166703698 @default.
• W2560392011 hasConcept C173396325 @default.
• W2560392011 hasConcept C2522874641 @default.
• W2560392011 hasConcept C2779690655 @default.
• W2560392011 hasConcept C2780727368 @default.
• W2560392011 hasConcept C2781018059 @default.
• W2560392011 hasConcept C29537977 @default.
• W2560392011 hasConcept C502942594 @default.
• W2560392011 hasConcept C54355233 @default.
• W2560392011 hasConcept C62112901 @default.
• W2560392011 hasConcept C67705224 @default.
• W2560392011 hasConcept C81885089 @default.
• W2560392011 hasConcept C86803240 @default.
• W2560392011 hasConceptScore W2560392011C104317684 @default.
• W2560392011 hasConceptScore W2560392011C119056186 @default.
• W2560392011 hasConceptScore W2560392011C1491633281 @default.
• W2560392011 hasConceptScore W2560392011C153911025 @default.
• W2560392011 hasConceptScore W2560392011C159047783 @default.
• W2560392011 hasConceptScore W2560392011C166703698 @default.
• W2560392011 hasConceptScore W2560392011C173396325 @default.
• W2560392011 hasConceptScore W2560392011C2522874641 @default.
• W2560392011 hasConceptScore W2560392011C2779690655 @default.
• W2560392011 hasConceptScore W2560392011C2780727368 @default.
• W2560392011 hasConceptScore W2560392011C2781018059 @default.
• W2560392011 hasConceptScore W2560392011C29537977 @default.
• W2560392011 hasConceptScore W2560392011C502942594 @default.
• W2560392011 hasConceptScore W2560392011C54355233 @default.
• W2560392011 hasConceptScore W2560392011C62112901 @default.
• W2560392011 hasConceptScore W2560392011C67705224 @default.
• W2560392011 hasConceptScore W2560392011C81885089 @default.
• W2560392011 hasConceptScore W2560392011C86803240 @default.
• W2560392011 hasIssue "1" @default.

• next