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• W2560562445 abstract "HEADINGS - Gastric cancer. Surgery, survival. ABSTRACT - Background: Gastric neoplasia is a heterogeneous and multifactorial disease and its incidence and mortality vary widely based on geographic location. Approximately 60% of the diagnoses of patients from occidental countries were made on the stages III and IV. The best treatment still is to realize a surgical procedure. Aim - Identify the epidemiological aspects of the patients diagnosed with T4b gastric adenocarcinoma. Methods - The study was observational, transversal and retrospective; it was also based on secondary sources from patients diagnosed with T4b gastric adenocarcinoma, through pathologic stages. A total of 815 charts were analyzed and 27 patients studied. The variables were: demographic aspects, main symptoms, risk factors, access to health system, surgical aspects, morbidity, mortality and survival. Results - Were included 22 men (81,5%) and five woman (18,5%), in the age group between 38 and 87 years old - median age of 58. The time, in months, to access the health system varied from one to 120, average of 12,5 months. The most prevalent signs and symptoms were: weight loss 23 (85,2%), epigastric pain 22 (81,5%), vomit 16 (59,3%) and gastric fullness 12 (44,4%). The frequency of the affected adjacent body structures was: pancreas 8 (29,6%), liver 7 (25,9%), transverse colon 6 (22,2%), small intestine 6 (22,2%), mesocolon 3 (11,1%), spleen 1 (3,7%) and gallbladder 1 (3,7%). Postoperative morbidity occurred in 51, 85% of the patients. There were a significative association between surgical mortality and the occurrence of fistula/ dehiscence, septic shock and bleeding. The survival rate after six months was 63,27%. Conclusion - The mean time between onset of symptoms and access to specialized health services was high. More than half of the patients had postoperative morbidities. Patients who had fistula / dehiscence, bleeding and septic shock were significantly associated with surgical mortality. The survival rate after six months was 63.27%. RESUMO - Racional: A neoplasia gastrica e doenca heterogenea e multifatorial, com incidencia e mortalidade variando geograficamente. Aproximadamente 60% dos diagnosticos em pacientes de paises ocidentais ocorrem nos estadios III ou IV. Nestes doentes, o melhor tratamento consiste na realizacao de procedimento cirurgico. Objetivo - Identificar os aspectos epidemiologicos de pacientes diagnosticados com adenocarcinoma gastrico T4b. Metodos - Estudo observacional, transversal, retrospectivo, de fonte secundaria, dos pacientes diagnosticados com adenocarcinoma gastrico T4b atraves de estadiamento patologico. Foram analisados 815 prontuarios, sendo 27 pacientes estudados. As variaveis investigadas foram: aspectos demograficos, principais queixas, fatores de risco, acesso ao servico de saude, aspectos cirurgicos, morbidade, mortalidade e sobrevida. Resultados - Vinte e dois eram homens (81,5%) e cinco mulheres (18,5%) com idade variando de 38 a 87 e media de 58,78 anos. O tempo de acesso ao servico, em meses, variou de 1 a 120, com media de 12,5. Os sinais e sintomas mais prevalentes foram: perda de peso 23 (85,2%), epigastralgia 22 (81,5%), vomitos 16 (59,3%) e plenitude gastrica 12 (44,4%). A frequencia de acometimento das estruturas adjacentes foi: pâncreas oito (29,6%), figado sete (25,9%), colon transverso seis (22,2%), intestino delgado seis (22,2%), mesocolon tres (11,1%), baco um (3,7%) e vesicula biliar um (3,7%). Morbidades pos-operatorias ocorreram em 51,85% dos pacientes. Houve associacao significativa entre mortalidade cirurgica e ocorrencia de fistula/deiscencia, choque septico e sangramento. A sobrevida ao final de seis meses foi de 63,27%. Conclusao - A media do tempo entre inicio dos sintomas e acesso ao servico de saude especializado foi elevada. Mais da metade dos pacientes apresentaram morbidades pos-operatorias. Os pacientes que apresentaram fistula/deiscencia, sangramentos e choque septico tiveram associacao significativa com mortalidade cirurgica. A sobrevida ao final de seis meses foi de 63,27%." @default.
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• W2560562445 date "2014-01-01" @default.
• W2560562445 modified "2023-09-26" @default.
• W2560562445 title "T4B GASTRIC CARCINOMA: 12 YEARS OF EXPERIENCE AT AN" @default.
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